| 王梦莹,唐迅,秦雪英,武轶群,李劲,高培,黄少平,李娜,杨冬立,任涛,吴涛,陈大方,胡永华.北方农村地区居民常见慢性非传染性疾病的家系队列研究进展[J].中华流行病学杂志,2018,39(1):94-97 |
| 北方农村地区居民常见慢性非传染性疾病的家系队列研究进展 |
| Progress in research of family-based cohort study on common chronic non-communicable diseases in rural population in northern China |
| 收稿日期:2017-07-14 出版日期:2018-01-13 |
| DOI：10.3760/cma.j.issn.0254-6450.2018.01.020 |
| 中文关键词: 高血压 脑卒中 糖尿病 家系队列研究 |
| 英文关键词: Hypertension Stroke Diabetes mellitus Family-based cohort study |
| 基金项目:国家自然科学基金（81230066，81102177，81172744，81473043） |
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| 中文摘要: |
| 家系队列研究是一种特殊的队列研究方法，以家系为单位收集研究对象的生物样本和环境暴露信息，并进行随访，为探索复杂性疾病病因研究中遗传、环境、基因-基因和基因-环境交互作用提供重要资源。本文将对“北方农村地区居民常见慢性非传染性疾病的家系队列研究”的目标、方法、初步结果、机遇与挑战进行简单介绍。 |
| 英文摘要: |
| Family-based cohort study is a special type of study design, in which biological samples and environmental exposure information of the member in a family are collected and related follow up is conducted. Family-based cohort study can be applied to explore the effect of genetic factors, environmental factors, gene-gene interaction, and gene-environment interaction in the etiology of complex diseases. This paper summarizes the objectives, methods and results, as well as the opportunities and challenges of the family-based cohort study on common chronic non-communicable diseases in rural population in northern China. |
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