文章摘要
孙凤,高乐,杨智荣,詹思延.偏倚风险评估系列:(五)非随机干预性研究[J].中华流行病学杂志,2018,39(3):374-381
偏倚风险评估系列:(五)非随机干预性研究
Series of risk of bias assessment (5): Risk Of Bias In Non-randomized Studies-of Interventions (ROBINS-I)
收稿日期:2017-07-04  出版日期:2018-03-21
DOI:10.3760/cma.j.issn.0254-6450.2018.03.024
中文关键词: 偏倚风险  评估工具  非随机干预性研究  观察性临床研究  系统综述
英文关键词: Risk of bias  Tool for assessment  Non-randomised Studies-of Interventions  Observational clinical study  Systematic review
基金项目:国家自然科学基金(71673003)
作者单位E-mail
孙凤 100191 北京大学公共卫生学院流行病与卫生统计学系
100191 北京大学循证医学中心 
 
高乐 100191 北京大学公共卫生学院流行病与卫生统计学系  
杨智荣 100191 北京大学循证医学中心  
詹思延 100191 北京大学公共卫生学院流行病与卫生统计学系
100191 北京大学循证医学中心 
siyan-zhan@bjmu.edu.cn 
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中文摘要:
      对非随机干预性研究(NRSI)偏倚评估工具ROBINS-I(Risk Of Bias In Non-randomised Studies-of Interventions)的主要内容进行详细介绍,并举例说明ROBINS-I的使用方法和注意事项。ROBINS-I针对NRSI的特点,设置了相应的评估领域和信号问题,为NRSI纳入系统综述进行证据整合提供偏倚风险信息。ROBINS-I为观察性研究和类实验领域新开发的评估工具,现已得到了一定程度的应用,但仍在进一步完善中,使用者可持续关注其后续更新与进展。
英文摘要:
      This paper summaries the Risk Of Bias In Non-randomized Studies-of Interventions (ROBINS-I), a tool for evaluating risk of bias about Non-randomized Studies-of Interventions (NRSI), and introduces the application of ROBINS-I in a published NRSI. According to the characteristics of NRSI, evaluation field and signaling question were designed in ROBINS-I to provide essential information about risk of bias for NRSI included in systematic reviews. ROBINS-I is the tool in assessment of risk of bias in observational studies and quasi-randomised studies. Although the tool has been used in practice to some extent, but it still needs further improvement. Attention should be paid to its update and progress.
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