文章摘要
张杜丹,唐迅,靳丹瑶,胡永华,高培.中国成年人糖尿病患病率Meta分析[J].中华流行病学杂志,2018,39(6):852-857
中国成年人糖尿病患病率Meta分析
Prevalence of diabetes in Chinese adults: a Meta-analysis
投稿时间:2017-11-17  
DOI:10.3760/cma.j.issn.0254-6450.2018.06.030
中文关键词: 糖尿病;患病率;Meta分析;成年人
英文关键词: Diabetes mellitus;Prevalence;Meta-analysis;Adults
基金项目:国家自然科学基金(81573226,91546120,81230066);北京市自然科学基金(7162107)
作者单位E-mail
张杜丹 100191 北京大学公共卫生学院流行病与卫生统计学系  
唐迅 100191 北京大学公共卫生学院流行病与卫生统计学系  
靳丹瑶 100191 北京大学公共卫生学院流行病与卫生统计学系  
胡永华 100191 北京大学医学信息学中心 yhhu@bjmu.edu.cn 
高培 100191 北京大学公共卫生学院流行病与卫生统计学系 peigao@bjmu.edu.cn 
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中文摘要:
      目的 采用Meta分析方法了解过去30年我国成年人糖尿病流行情况,为糖尿病的预防和控制提供科学依据。方法 检索中国期刊全文数据库(CNKI)、万方数据资源系统(Wanfang)、维普数据库(VIP)和PubMed数据库截至2017年10月1日收录的所有有关中国多省市糖尿病患病率研究的文献。运用随机效应模型计算合并患病率。若存在异质性,采用连续分段多项式回归模型来估计糖尿病患病率随时间变化趋势。结果 共纳入15篇文献,其中2篇文献因仅包括≥ 40岁人群未纳入主要分析。Meta分析显示,1980-2013年中国成年人糖尿病患病率为6.3%(95%CI:4.6%~8.0%),城市合并患病率高于农村地区,男性糖尿病合并患病率略高于女性。1980-2013年,我国成年人糖尿病患病率呈非线性增长。2000年前的合并患病率为3.5%(95%CI:2.0%~4.9%),每年增长约0.17%;2000年后的合并患病率为8.0%(95%CI:6.0%~10.1%),每年增加约0.72%。结论 中国成年人糖尿病患病率不断升高,且在2000年后迅速增长,需采取积极的策略预防和控制糖尿病。
英文摘要:
      Objective To evaluate the prevalence and trend of diabetes mellitus among Chinese adults during the past thirty years.Methods Papers, published before October 1, 2017 and related to the prevalence of diabetes mellitus among Chinese adults, were searched through PubMed, China Knowledge Resource Integrated Database, Wanfang Digital Database and VIP Citation Databases. Stata 13.0 software was used to estimate the prevalence of diabetes mellitus, with pooled prevalence calculated based on random effects. Subgroup analysis was conducted based on time, sex, areas and body mass index groups of investigation. Continuous fractional polynomial regression model on the midpoint of each survey period, weighted by the number of participants in each study, was used to estimate and illustrate the trends of prevalence of diabetes over the years.Results In total, 15 studies were included and two of them were excluded in the primary analysis with the age limitation of participants as ≥ 40 years old, for recruitment. The average prevalence of diabetes among Chinese adults was 6.3% (95% CI:4.6%-8.0%), during the past thirty years. The pooled prevalence appeared higher in urban than in rural areas and higher in men than in women. Between 1980 and 2013, the increase of Chinese diabetes prevalence did not follow the linear trend. Before 2000, the average prevalence showed as 3.5% (95% CI:2.0%-4.9%), with an annual increase rate as 0.17%. Since 2000, the average annual prevalence of diabetes mellitus had appeared around 8.0% (95% CI:6.0%-10.1%), with an annual growth rate of 0.72% (95% CI:0.34%-1.10%).Conclusion The prevalence of diabetes in Chinese adults had been rapidly increasing since the year 2000, indicating that efforts should be strengthened for diabetes prevention, in China.
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