文章摘要
纪文静,梁爱民,曲成毅,沈瑞云,魏庄,马扬.中国7个城市婴幼儿常见胃肠道不适症状流行病学特征现况调查[J].中华流行病学杂志,2018,39(9):1179-1183
中国7个城市婴幼儿常见胃肠道不适症状流行病学特征现况调查
Epidemiologic survey on the prevalence and distribution of infants' common gastrointestinal symptoms in 7 cities in China: a population-based study
投稿时间:2017-10-25  
DOI:10.3760/cma.j.issn.0254-6450.2018.09.007
中文关键词: 胃肠道症状;反流;肠绞痛;便秘;流行病学;婴幼儿
英文关键词: Gastrointestinal symptom;Regurgitation;Infantile colic;Constipation;Epidemiology;Infants
基金项目:
作者单位E-mail
纪文静 100045 北京, 国家儿童医学中心 首都医科大学附属北京儿童医院保健中心  
梁爱民 100045 北京, 国家儿童医学中心 首都医科大学附属北京儿童医院保健中心 liang-aimin@163.com 
曲成毅 030001 太原, 山西医科大学公共卫生学院  
沈瑞云 100045 北京, 国家儿童医学中心 首都医科大学附属北京儿童医院保健中心  
魏庄 100045 北京, 国家儿童医学中心 首都医科大学附属北京儿童医院保健中心  
马扬 100045 北京, 国家儿童医学中心 首都医科大学附属北京儿童医院保健中心  
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中文摘要:
      目的 对中国7个城市0~3岁婴幼儿常见的胃肠道不适症状进行现况调查,探讨婴幼儿常见胃肠道不适症状的患病率和流行病学特征。方法 应用分层、整群随机抽样方法对中国7城市0~3岁常住婴幼儿进行问卷调查,根据调查结果,按国际通用的婴幼儿功能性胃肠病Rome Ⅳ诊断标准判断常见胃肠道不适症状的患病率,并分析其地域、城乡、年龄和性别分布特征。结果 共回收有效问卷20 932份。0~1岁婴儿共10 193人,出现反流者共1 960人,患病率为19.2%,0~3月龄婴儿反流的患病率最高(29.8%),之后随年龄增加逐渐降低,不同年龄组间差异有统计学意义。0~5月龄婴儿共4 470人,出现肠绞痛者共325人,患病率为7.3%,1~2月龄婴儿肠绞痛的患病率最高(10.0%),不同年龄组婴儿肠绞痛的患病率差异有统计学意义。在0~3岁婴幼儿中,功能性便秘者1 755人,患病率为8.4%,0~3月龄婴儿患病率最低(6.2%),30~36月龄婴儿患病率最高(10.0%),不同年龄组间便秘的患病率差异有统计学意义。结论 反流、肠绞痛、功能性便秘等胃肠道症状在健康婴幼儿中普遍存在,患病率有明显的年龄差异特点。
英文摘要:
      Objective Regurgitation, infantile colic, and functional constipation are common gastrointestinal symptoms in childhood, the aim of this study was to explore the prevalence and distribution of these symptoms in China. Methods A screening program in infants aged 0 to 3 years selected through stratified cluster random sampling was carried out in 7 cities in China. Questionnaires were filled, and then diagnosis were made according to Rome Ⅳ criteria. Areas, (urban-rural), age and gender distribution of prevalence of childhood common gastrointestinal symptoms were analyzed. Results Totally, 20 932 effective questionnaires were returned. The total number of infants aged 0 to 1 years was 10 193. Regurgitation was diagnosed in 1 960 infants, with the prevalence of 19.2%, among infants aged 0 to 3 months that had highest prevalence (29.8%). The prevalence decreased with age, and differences among different age groups showed significant. For infantile colic, 4 470 infants aged 0 to 5 months were analyzed and the prevalence of infantile colic was 7.3%. The prevalence of infantile colic was the highest in infants aged 1 to 2 months (10.0%). Age specific difference was significant. Of all the infants, functional constipation was diagnosed in 1 755 infants with the prevalence of 8.4%, and the lowest prevalence was found in infants aged 0 to 3 months (6.2%), and the highest prevalence was in infants aged 30 to 36 months (10.0%). The differences in different age group were significant. Conclusion Symptoms of regurgitation, infantile colic, and functional constipation are common in infants in China, with age specific difference in prevalence of the symptoms.
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