文章摘要
甘秀敏,马烨,豆智慧,赵德才,吴亚松,赵燕,于兰.中国2011-2015年跨省流动HIV/AIDS免费抗病毒治疗现状及影响因素分析[J].中华流行病学杂志,2018,39(9):1234-1238
中国2011-2015年跨省流动HIV/AIDS免费抗病毒治疗现状及影响因素分析
Current status of national free antiretroviral therapy in interprovincial migrating people living with HIV/AIDS and influencing factors, China, 2011-2015
投稿时间:2018-01-31  
DOI:10.3760/cma.j.issn.0254-6450.2018.09.017
中文关键词: 艾滋病病毒感染者/艾滋病患者;跨省流动;抗病毒治疗;影响因素
英文关键词: People living with HIV/AIDS;Interprovincial migration;Antiretroviral therapy;Influencing factor
基金项目:中国疾病预防控制中心性病艾滋病预防控制中心青年科研基金(2018AFQN006)
作者单位E-mail
甘秀敏 102206 北京, 中国疾病预防控制中心性病艾滋病预防控制中心  
马烨 102206 北京, 中国疾病预防控制中心性病艾滋病预防控制中心 artinfo@chinaaids.cn 
豆智慧 102206 北京, 中国疾病预防控制中心性病艾滋病预防控制中心  
赵德才 102206 北京, 中国疾病预防控制中心性病艾滋病预防控制中心  
吴亚松 102206 北京, 中国疾病预防控制中心性病艾滋病预防控制中心  
赵燕 102206 北京, 中国疾病预防控制中心性病艾滋病预防控制中心  
于兰 102206 北京, 中国疾病预防控制中心性病艾滋病预防控制中心  
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中文摘要:
      目的 分析我国跨省流动艾滋病病毒感染者/艾滋病患者(HIV/AIDS)免费抗病毒治疗现状及其影响因素。方法 利用2011-2015年全国艾滋病综合防治信息系统工作数据,采用描述性和趋势检验分析跨省流动HIV/AIDS抗病毒治疗历年变化趋势和主要特征,logistic回归分析探讨影响该人群抗病毒治疗覆盖面的主要因素。结果 跨省流动HIV/AIDS占比从2011年的7.1%(17 784/250 645)提高到2015年的10.3%(54 596/528 226)(Z=51.38,P<0.000 1),跨省流动HIV/AIDS抗病毒治疗比例由2011年的37.3%(6 641/17 784)逐步上升到2015年的71.0%(38 783/54 596)(Z=96.23,P<0.000 1),已与2015年非跨省流动HIV/AIDS抗病毒治疗比例接近(71.5%,338 654/473 630)。多因素logistic回归分析显示,跨省流动HIV/AIDS中,女性、≥50岁年龄组、汉族、已婚/有配偶、高中/中专及以上文化程度、男男性行为感染、首次随访CD4+T淋巴细胞计数≤500个/μl、通过医疗机构检测或重点人群检测发现HIV感染者、现住址在城市者抗病毒治疗比例较高。结论 不同特征的跨省流动HIV/AIDS抗病毒治疗比例不同,需采取有效措施进一步扩大抗病毒治疗覆盖面,尽早将跨省流动HIV/AIDS纳入抗病毒治疗规范化管理系统。
英文摘要:
      Objective To understand the current status of national free antiretroviral therapy in interprovincial migrating people living with HIV/AIDS (PLWHA) and influencing factors in China. Methods Descriptive and trend test analyses were performed to evaluate the historical characteristics and trends of main descriptive indicators on national free antiretroviral therapy for the interprovincial migrating PLWHA by using the data collected from National Comprehensive HIV/AIDS Information System from 2011 to 2015. Logistic regression model was used to explore the main factors that influencing the coverage of national free antiretroviral therapy among the interprovincial migrating PLWHA in China. Results The proportion of interprovincial migrating PLWHA gradually increased in last 5 years from 7.1% (17 784/250 645) in 2011 to 10.3% (54 596/528 226) in 2015 (Z=51.38, P<0.000 1) in China. The coverage rate of free antiretroviral therapy in interprovincial migrating PLWHA increased from 37.3% (6 641/17 784) in 2011 to 71.0% (38 783/54 596) in 2015, showing a significant rising tendency (Z=96.23, P<0.000 1), but it was slightly lower than that in non-interprovincial migrating PLWHA in 2015 (71.5%, 338 654/473 630). Multivariate logistic regression analysis showed that the PLWHA who were females, aged ≥ 50 years, of Han ethnic group, married or had spouse, had the educational level of high school or above, infected through homosexual intercourse, with CD4+T cells counts ≤ 500 cells/μl at the first visit, identified to be infected with HIV in medical setting, living in urban areas et al, were more likely to receive free antiretroviral therapy. Conclusions The coverage rate of free antiretroviral therapy varied among the interprovincial migrating PLWHA with different characteristics. It is still necessary to take effective measures to further increase the coverage of free antiretroviral therapy in interprovincial migrating PLWHA and to include the free antiretroviral therapy in interprovincial migrating PLWHA into standardized management system as soon as possible.
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