文章摘要
金珊珊,于波,闫世春,孙巍,崔晓明,周雪,杨丽秋,那立欣,郭彧,卞铮,李立明,陈铮鸣.哈尔滨市人群饥荒暴露对中老年期慢性病患病风险的影响[J].中华流行病学杂志,2018,39(10):1314-1318
哈尔滨市人群饥荒暴露对中老年期慢性病患病风险的影响
Effect of famine exposure on the risk of chronic disease in later life among population in Harbin
投稿时间:2017-12-25  
DOI:10.3760/cma.j.issn.0254-6450.2018.10.005
中文关键词: 饥荒暴露;慢性病;回顾性队列研究
英文关键词: Famine exposure;Chronic disease;Retrospective cohort study
基金项目:国家重点研发计划精准医学研究重点专项(2016YFC0900500,2016YFC0900501,2016YFC0900504);中国香港Kadoorie Charitable基金;英国Wellcome Trust(202922/Z/16/Z,088158/Z/09/Z,104085/Z/14/Z)
作者单位E-mail
金珊珊 150081 哈尔滨医科大学
150056 哈尔滨市南岗区疾病预防控制中心 
 
于波 150056 哈尔滨市南岗区疾病预防控制中心  
闫世春 150036 哈尔滨, 黑龙江省疾病预防控制中心  
孙巍 150036 哈尔滨, 黑龙江省疾病预防控制中心  
崔晓明 150036 哈尔滨, 黑龙江省疾病预防控制中心  
周雪 150036 哈尔滨, 黑龙江省疾病预防控制中心 snowweek@hotmail.com 
杨丽秋 150056 哈尔滨市南岗区疾病预防控制中心 ngqmanbing@163.com 
那立欣 150081 哈尔滨医科大学  
郭彧 100730 北京, 中国医学科学院  
卞铮 100730 北京, 中国医学科学院  
李立明 100191 北京大学公共卫生学院  
陈铮鸣 OX3 7LF英国牛津大学临床与流行病学研究中心纳菲尔德人群健康系  
摘要点击次数: 145
全文下载次数: 104
中文摘要:
      目的 研究哈尔滨市人群的饥荒暴露对中老年期糖尿病、肥胖、高血压、冠心病和脑卒中等慢性病患病风险的影响。方法 以中国慢性病前瞻性研究(China Kadoorie Biobank,CKB)项目哈尔滨市的基线调查人群为研究对象,采用回顾性队列研究设计,应用logistic分析比较饥荒暴露人群与非饥荒暴露人群中老年期糖尿病、肥胖、高血压、冠心病和脑卒中等慢性病患病风险的差异。结果 调整影响因素后,饥荒暴露人群的肥胖(OR=1.204,95% CI:1.104~1.313,P<0.01)、高血压(OR=1.315,95% CI:1.210~1.429,P<0.01)和冠心病(OR=1.495,95% CI:1.369~1.632,P<0.01)的危险性高于非饥荒暴露人群。饥荒暴露年龄越小,中老年期各种慢性病发生风险越大。结论 饥荒暴露是肥胖、高血压和冠心病的危险因素。保证生命全过程,尤其是生命早期和青少年期的营养充足对预防中老年期肥胖、高血压和冠心病具有重要意义。
英文摘要:
      Objective To study the relations between famine exposure and the risk of chronic diseases as diabetes mellitus, obesity, hypertension, coronary heart disease and stroke in the population of Harbin. Methods Our data was collected from the baseline survey-the China Kadoorie Biobank project (CKB) in Harbin. Retrospective cohort study design was used. Related risks on chronic diseases including diabetes mellitus, obesity, hypertension, coronary heart disease and stroke, were compared among the famine exposed or non-exposed people, respectively by logistic analysis method. Results After adjusted for factors as age, sex, physical activity, smoking, alcohol intake, diet, family history of diseases, it appeared that the factor ‘famine exposure’ had increased the risks of diseases as obesity (OR=1.204, 95% CI:1.104-1.313, P<0.01), hypertension (OR=1.315, 95% CI:1.210-1.429, P<0.01) and coronary heart disease (OR=1.495, 95% CI:1.369-1.632, P<0.01). The lower the age of population being exposed to famine, the greater the risk of the development of all kinds of chronic diseases. Conclusions Famine exposure appeared a risk factor for obesity, hypertension, and coronary heart disease. It is of great significance to ensure the life-long nutrition of the people, especially in the early and adolescent stages, to prevent obesity, hypertension, and coronary heart disease in their later lives.
查看全文   Html全文     查看/发表评论  下载PDF阅读器
关闭