| 陆凤,应丹妮,龚巍巍,郑维晖,何青芳,方乐,钟节鸣,俞敏.浙江省甲状腺癌患病影响因素的配对病例对照研究[J].中华流行病学杂志,2018,39(10):1387-1393 |
| 浙江省甲状腺癌患病影响因素的配对病例对照研究 |
| Factors related to thyroid carcinoma in Zhejiang province: a matched case-control study |
| 收稿日期:2018-02-21 出版日期:2018-10-23 |
| DOI：10.3760/cma.j.issn.0254-6450.2018.10.018 |
| 中文关键词: 甲状腺癌 影响因素 配对病例对照研究 |
| 英文关键词: Thyroid carcinoma Influencing factors Matched case-control study |
| 基金项目:国家卫生和计划生育委员会科研基金-浙江省医药卫生重大科技计划（WKJ-ZJ-1506） |
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| 中文摘要: |
| 目的 了解浙江省甲状腺癌患病的影响因素。方法 采用配对病例对照研究方法，对659对甲状腺癌病例对照者进行统一问卷调查。采用单因素和多因素条件logistic回归分析甲状腺癌的影响因素。结果 多因素条件logistic回归分析结果表明，较高的文化程度、糖尿病病史、饮酒、饮茶、职业性体力活动、经常食用水产/海鲜类和蛋类能降低甲状腺癌患病的风险；精神压抑、CT检查史、口味偏淡等因素能增加甲状腺癌患病的风险。性别分层发现，饮酒、饮茶、职业性体力活动、食用蛋类能降低男性甲状腺癌的患病风险；较高的文化程度、糖尿病病史、饮茶、经常食用水产/海鲜类、经常食用蛋类、女性月经持续天数短能降低女性甲状腺癌患病的风险。结论 文化程度高、糖尿病病史、饮酒、饮茶、职业性体力活动、经常食用水产/海鲜类、蛋类、精神压抑、CT检查史、口味偏淡可能为甲状腺癌患病的主要影响因素。 |
| 英文摘要: |
| Objective To explore the influencing factors related to thyroid carcinoma. Methods Matched by sex, age and original residential areas, 659 pairs of cases and controls were recruited and studied. Methods including both single factor analysis and multivariate conditional logistic regression analysis were carried out to identify the influencing factors. Results Multivariate conditional logistic regression analysis showed that higher education, being diabetic, alcohol intake, tea drinking, occupational physical activity and the frequency of eating fishes/eggs etc., were potentially protective to thyroid carcinoma. Depression, personal history of CT examination and less salt intake seemed to be risk factors on thyroid carcinoma. For males, factors as alcohol intake, tea drinking, occupational physical activity and frequent egg-eating appeared protective. For females, higher education, diabetes, tea drinking, occupational physical activity, frequent consumption of fishes/eggs, short duration of menstruation appeared as possibly protective. Conclusion Higher education, diabetes, alcohol intake, tea drinking, occupational physical activity, frequent consumption of fishes/eggs, depression, personal history of CT examination and less salt intake served as potential influencing factors to thyroid carcinoma. |
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