文章摘要
李正禹,武继磊,李佳佳,裴丽君.慢性病对中国65岁及以上老年人日常活动能力影响的队列研究[J].中华流行病学杂志,2019,40(1):33-40
慢性病对中国65岁及以上老年人日常活动能力影响的队列研究
A cohort study on the influence of the chronic diseases on activities of daily living of the elderly aged 65 years and over in China
投稿时间:2018-07-04  
DOI:10.3760/cma.j.issn.0254-6450.2019.01.008
中文关键词: 慢性疾病;日常活动能力;队列研究;老年人
英文关键词: Chronic and non-communicable disease;Activities of daily living;Cohort study;Elderly population
基金项目:国家自然科学基金(41871360);2015年达能营养中心膳食营养研究与宣教基金(DIC2015-05)
作者单位E-mail
李正禹 北京大学人口研究所 100871  
武继磊 北京大学人口研究所 100871  
李佳佳 北京大学人口研究所 100871  
裴丽君 北京大学人口研究所 100871 peilj@pku.edu.cn 
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中文摘要:
      目的 探讨5类高发慢性病及慢性病患病数目对老年人日常活动能力(ADL)的影响。方法 将2002年中国老年健康影响因素跟踪调查访问的10 501名老年人的调查信息作为基线数据,随访该队列人群至2014年,采用Cox比例风险模型分析5类高发慢性病及慢性病患病数目对不同年龄组老年人ADL的影响。结果 与不患任何慢性疾病的老年人比较,患高血压可增加各个年龄组老年人的ADL受损风险,65~74岁组增加43%(HR=1.43,95% CI:1.14~1.79),75~89岁组增加21%(HR=1.21,95% CI:1.02~1.43),90~105岁组增加20%(HR=1.20,95% CI:1.02~1.43);患糖尿病使65~74岁组老年人ADL受损风险增加102%(HR=2.02,95% CI:1.29~3.17),患脑血管病使ADL受损风险增加79%(HR=1.79,95% CI:1.24~2.58);在整个老年群体中,患1种慢性病使ADL受损风险增加13%(HR=1.13,95% CI:1.02~1.25),患≥ 2种慢性病使ADL受损风险增加25%(HR=1.25,95% CI:1.13~1.40);患≥ 2种慢性病使65~74、75~89岁老年人ADL受损风险分别增加50%(HR=1.50,95% CI:1.21~1.87)、17%(HR=1.17,95% CI:1.01~1.38)。结论 高血压是导致老年人ADL受损的重要危险因素;65~74岁组老年人患高血压、糖尿病、脑血管病或多种慢性病共患均可增加其ADL受损风险。
英文摘要:
      Objective To understand the influence of chronic diseases on the risk of impaired activities of daily living (ADL) of the elderly. Methods Baseline data of 10 501 elderly individuals recruited by the Chinese Longitudinal Healthy Longevity Survey in 2002 were used, and follow up for this population was conducted until 2014. Cox Proportional Hazard Model was used to estimate the hazards ratios (HR) for the associations between five kinds of chronic diseases, the number of chronic diseases and the risk of ADL impairment in different age groups of the elderly. Results Hypertension increased the risk of ADL impairment in the elderly of all age groups, which increased the ADL impaired risk by 43% (HR=1.43, 95% CI:1.14-1.79) in group aged 65-74 years, 21% (HR=1.21, 95% CI:1.02-1.43) in group aged 75-89 years and 20% (HR=1.20, 95% CI:1.02-1.43) in group aged 90-105 years, respectively. Diabetes and cerebrovascular disease increased the ADL impaired risk by 102%(HR=2.02, 95% CI:1.29-3.17), and 79% (HR=1.79, 95% CI:1.24-2.58) in group aged 65-74 years, respectively. ‘Suffering from one chronic disease’ increased the ADL impaired risk by 13% (HR=1.13, 95% CI:1.02-1.25), and suffering from two or more chronic diseases increased the ADL impaired risk by 25% (HR=1.25, 95% CI:1.13-1.40) in all the age groups. Suffering from two or more chronic diseases increased the ADL impaired risk by 50% (HR=1.50, 95% CI:1.21-1.87) in group aged 65-74 years and 17% (HR=1.17, 95% CI:1.01-1.38) in groups aged 75-89 years. Conclusions Hypertension was one of the most important risk factors for the impaired ADL in the elderly population in all age groups. Hypertension, diabetes, cerebrovascular disease or comorbidity increased the risk of impaired ADL in group aged 65-74 years.
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