| 吴俣,刘珏,刘民.孕妇乙型肝炎病毒感染及对母婴安全影响的研究进展[J].中华流行病学杂志,2019,40(7):854-858 |
| 孕妇乙型肝炎病毒感染及对母婴安全影响的研究进展 |
| Progress in research of effect of pregnancy complicated with hepatitis B virus infection on maternal and infant safety |
| 收稿日期:2019-03-12 出版日期:2019-07-17 |
| DOI：10.3760/cma.j.issn.0254-6450.2019.07.022 |
| 中文关键词: 乙型肝炎病毒 妊娠妇女 流行病学 |
| 英文关键词: Hepatitis B virus Pregnant women Epidemiology |
| 基金项目:国家自然科学基金（71874003，81703240） |
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| 中文摘要: |
| HBV感染是重要的公共卫生问题之一。全球孕妇HBsAg阳性率存在地区差异，从低流行地区的0.6%到高流行地区的20%。我国孕妇HBsAg阳性率高于全球平均水平。近年来多项研究发现妊娠妇女合并HBV感染不仅增加母婴传播风险，同时也会给孕妇及其子代带来不良影响。为此，本研究从孕妇HBsAg阳性率、妊娠合并HBV感染对孕妇和围产儿的影响等方面对国内外研究进展进行综述，以期探讨孕妇HBV感染对母婴安全的影响。 |
| 英文摘要: |
| Hepatitis B virus (HBV) infection is one of the important public health problems. In order to eliminate the threat of viral hepatitis to public health, World Health Organization has proposed to achieve the goal of reducing the HBsAg positive rate in children to 0.1% by 2030. There are regional differences in HBsAg positive rates among pregnant women worldwide, from 0.6% in areas with low prevalence to 20% in areas with high prevalence. The positive rate of HBsAg in pregnant women in China is higher than global average. In recent years, several studies have found that HBV infection in pregnancy not only increase the risk of mother-to-child transmission, but also adversely affect the health of pregnant women and their children. Therefore, this paper summarizes the progress in research both at home and abroad in terms of HBsAg positive rate in pregnant women and the influence of pregnancy complicated with HBV infection on pregnant women and perinatal infants in order to explore the effect of pregnancy complicated with HBV infection on maternal and infant safety. |
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