文章摘要
张晗希,韩孟杰,周郁,修翔飞,徐芳,王璐.我国50岁及以上人群HIV感染率的Meta分析[J].中华流行病学杂志,2020,41(1):96-102
我国50岁及以上人群HIV感染率的Meta分析
HIV infection rate in people aged 50 years and older in China: a Meta-analysis
收稿日期:2019-04-23  出版日期:2020-01-14
DOI:10.3760/cma.j.issn.0254-6450.2020.01.018
中文关键词: 艾滋病病毒;感染;Meta分析;50岁及以上人群
英文关键词: HIV;Infection;Meta-analysis;People aged 50 years and above
基金项目:
作者单位E-mail
张晗希 中国疾病预防控制中心性病艾滋病预防控制中心, 北京 102206  
韩孟杰 中国疾病预防控制中心性病艾滋病预防控制中心, 北京 102206  
周郁 中国疾病预防控制中心性病艾滋病预防控制中心, 北京 102206  
修翔飞 中国疾病预防控制中心性病艾滋病预防控制中心, 北京 102206  
徐芳 中国疾病预防控制中心性病艾滋病预防控制中心, 北京 102206  
王璐 中国疾病预防控制中心性病艾滋病预防控制中心, 北京 102206 wanglu64@163.com 
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中文摘要:
      目的 我国≥ 50岁人群艾滋病疫情呈上升趋势,已成为艾滋病防治的关注重点。本研究运用Meta分析法综合评估我国≥ 50岁人群HIV感染状况及其时间和地区分布,为该人群艾滋病预防干预提供科学依据。方法 文献检索数据库包括万方数据资源系统、中国期刊全文数据库(CNKI)、PubMed和Embase数据库。对各数据库所检索出的文章进行筛选和数据提取,运用R Studio1.1.456软件计算合并HIV感染率,并评估发表偏倚。结果 本研究共纳入30篇文献,研究地区覆盖全国13个省(市、自治区)。结果显示,2010-2018年≥ 50岁人群HIV感染率为1.68%(95%CI:1.00%~2.79%)。按照地区进行亚组分析中,东部地区HIV感染率(2.60%)高于中、西部地区(0.16%、2.13%)。结论 我国≥ 50岁人群HIV感染率总体较高,控制该人群中HIV的感染,对遏制中国艾滋病的流行有重要意义。
英文摘要:
      Objective The prevalence of HIV/AIDS in people aged ≥ 50 years is increasing in China, resulting in another focus for AIDS prevention and control. A Meta-analysis was conducted to evaluate the HIV infection, its area and time distributions in people aged ≥ 50 years in China to provide evidence for the prevention and control of HIV/AIDS. Methods Information on HIV infection rate in people aged ≥ 50 years in China were collected from Wanfang digital database, China National Knowledge Infrastructure (CNKI), PubMed and Embase. The R Studio1.1.456 software was used to calculate the pooled infection rate, and assessed the publication bias. Results A total of 30 studies which covered 13 provinces were selected. From 2010 to 2018, the pooled HIV infection rate in people aged ≥ 50 years was 1.68% (95%CI:1.00%-2.79%). The HIV infection rate (2.60%) was higher in eastern China than in central and western China (0.16%, 2.13%). Conclusion The overall HIV infection rate in people aged ≥ 50 years is generally high in China. It is important to control the HIV infection in this population to facilitate the AIDS prevention and control in China.
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