文章摘要
岳和欣,冯雅慧,吴散散,王雅文,蔡姝雅,石英杰,陈云利,湛永乐,马良坤,江宇.孕期妇女体力活动变化对抑郁影响的队列研究[J].中华流行病学杂志,2020,41(6):834-838
孕期妇女体力活动变化对抑郁影响的队列研究
Effects of changes in physical activities on depressive symptoms during pregnancy: a cohort study
收稿日期:2020-01-18  出版日期:2020-06-16
DOI:10.3760/cma.j.cn112338-20200118-00043
中文关键词: 体力活动;抑郁;孕期;队列研究
英文关键词: Physical activity;Depressive symptoms;Pregnancy;Cohort study
基金项目:中国医学科学院医学与健康科技创新工程(2019-I2M-2-007)
作者单位E-mail
岳和欣 中国医学科学院/北京协和医学院公共卫生学院, 北京 100730  
冯雅慧 中国医学科学院/北京协和医学院公共卫生学院, 北京 100730  
吴散散 中国医学科学院/北京协和医学院公共卫生学院, 北京 100730  
王雅文 中国医学科学院/北京协和医学院公共卫生学院, 北京 100730  
蔡姝雅 中国医学科学院/北京协和医学院公共卫生学院, 北京 100730  
石英杰 中国医学科学院/北京协和医学院公共卫生学院, 北京 100730  
陈云利 中国医学科学院/北京协和医学院公共卫生学院, 北京 100730  
湛永乐 中国医学科学院/北京协和医学院公共卫生学院, 北京 100730  
马良坤 中国医学科学院/北京协和医学院北京协和医院妇产科, 北京 100730  
江宇 中国医学科学院/北京协和医学院公共卫生学院, 北京 100730 jiangyu@pumc.edu.cn 
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中文摘要:
      目的 探究孕妇在孕早-中期体力活动变化对孕中期抑郁的影响。方法 依托中国孕产妇队列研究·协和项目(2017年7月25日至2018年11月26日),将有效完成孕早、中期体力活动和抑郁情况调查的2 454名孕妇纳入研究。采用国际体力活动短问卷和爱丁堡产后抑郁量表,调查研究对象孕早期和孕中期的体力活动和抑郁情况。以孕早期是否患有抑郁作分组。采用非条件logistic回归分析孕早期不患抑郁组的孕早、中期体力活动变化对预防孕中期抑郁的作用,在孕早期抑郁组中分析孕早、中期体力活动变化对减缓孕中期抑郁的作用。结果 孕妇基线和孕中期抑郁的检出率分别为23.83%和20.57%。调整年龄、文化程度、职业、家庭年收入和孕前BMI等因素后,logistic回归结果显示,对于基线不抑郁的孕妇,孕期增加和保持充足的体力活动能够预防孕中期抑郁(OR=0.479,95% CI:0.335~0.684;OR=0.566,95% CI:0.394~0.815),但对于基线抑郁的孕妇,体力活动与减缓孕中期抑郁的相关性差异无统计学意义(P>0.05)。结论 孕期妇女增加和保持充足的体力活动对于抑郁有预防的作用,但对于孕早期已患抑郁的妇女来说,缓解效果不明显。应在鼓励孕妇加强体力活动的同时,开展抑郁筛查,以减少孕期抑郁的发生。
英文摘要:
      Objective To investigate the effect of changes in physical activities on depressive symptoms in the second trimester of pregnancy. Methods Data from the Chinese Pregnant Women Cohort Study, from July 25, 2017 to November 26, 2018, were used. Women who had effectively completed the survey of physical activity and depressive symptoms in the first and second trimesters of pregnancy, were recruited. Both International Physical Activity Questionnaire-short and Edinburgh Postnatal Depression Scale were used, respectively. Pregnant women who had completed two surveys were included in our study and were divided into two groups according to the depressive symptoms, measured at the baseline. Among the pregnant women without depressive symptoms at the baseline, logistic regression was used to analyze the effects of changes in physical activity on the prevention of depressive symptoms. Effect on the reduction of depressive symptoms was analyzed, using the same method. Results The prevalence rates of depressive symptoms were 23.83% and 20.57% in the baseline and second trimester, respectively. After adjusting for age, education level, occupation, family annual income and pre-pregnancy BMI, data from the logistic regression showed that women without depressive symptoms and with increased and adequate physical activities in the baseline, were with lower risks to develop depressive symptoms in the second trimester (OR=0.479, 95%CI: 0.335-0.684;OR=0.566, 95%CI: 0.394-0.815). Among women with depressive symptoms in the baseline survey, association between physical activity and depressive symptoms was not statistically significant (P>0.05). Conclusions Increased and adequate physical activities showed preventive effects on depressive symptoms during pregnancy, but the remission effect was not obvious in women with depressive symptoms. Pregnant women should be encouraged to increase their physical activities while screening programs should also be carried out to reduce the depressive symptoms during pregnancy.
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