文章摘要
赵晶晶,张汀汀,刘晓华,孙纪新,刘玉环,岳福娟,张帆,曹亚景.睡眠时间与成年人代谢综合征相关性的Meta分析[J].中华流行病学杂志,2020,41(8):1272-1279
睡眠时间与成年人代谢综合征相关性的Meta分析
A Meta-analysis on the association between sleep duration and metabolic syndrome in adults
收稿日期:2020-01-06  出版日期:2020-08-25
DOI:10.3760/cma.j.cn112338-20200106-00013
中文关键词: 睡眠时间;代谢综合征;Meta分析;观察性研究
英文关键词: Sleep duration;Metabolic syndrome;Meta-analysis;Observational study
基金项目:河北省医学科学研究课题(20200697)
作者单位E-mail
赵晶晶 河北省疾病预防控制中心慢性非传染性疾病防治所, 石家庄 050021  
张汀汀 河北省疾病预防控制中心寄生虫防治所, 石家庄 050021  
刘晓华 北京维世达诊所, 北京 100020  
孙纪新 河北省疾病预防控制中心慢性非传染性疾病防治所, 石家庄 050021  
刘玉环 河北省疾病预防控制中心慢性非传染性疾病防治所, 石家庄 050021  
岳福娟 河北省疾病预防控制中心慢性非传染性疾病防治所, 石家庄 050021  
张帆 河北省疾病预防控制中心慢性非传染性疾病防治所, 石家庄 050021  
曹亚景 河北省疾病预防控制中心慢性非传染性疾病防治所, 石家庄 050021 191419688@qq.com 
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中文摘要:
      目的 对睡眠时间与成年人MS之间的关系进行定量评估,以期为MS的防治提供科学依据。方法 检索中英文数据库,纳入2019年10月以前已发表的相关文献。采用Stata 11.0软件对纳入的文献进行Meta分析。结果 最终纳入38篇文献,包含研究对象共计656 319例,其中MS患者共150 638例。睡眠时间与MS存在“U”形关联,短睡眠时间者患MS风险是正常睡眠者的1.11倍(95% CI:1.07~1.16),长睡眠时间者患MS风险是正常睡眠者的1.10倍(95% CI:1.03~1.18)。亚组分析显示,横断面研究中,相对于正常睡眠时间组,短睡眠时间使男性、<60岁人群、亚洲人及白种人患MS风险分别增加6%、14%、9%和24%,长睡眠时间使女性和<60岁人群患MS风险分别增加13%和19%。队列研究中观察到亚洲人短睡眠时间与MS呈正相关(RR=1.10,95% CI:1.07~1.13),白种人长睡眠时间与MS呈正相关(RR=1.56,95% CI:1.08~2.26)。结论 MS与长睡眠时间和短睡眠时间之间均存在关联。睡眠是可以改变的行为习惯,因此通过干预睡眠以降低MS患病风险具有重要的公共卫生意义。
英文摘要:
      Objective To quantitatively evaluate the relationship between sleep duration and metabolic syndrome in adults in order to set up programs on prevention and treatment of metabolic syndrome in this population. Methods Relevant studies were identified by systematically searching databases before October 2019. All statistical analyses were under the use of Stata 11.0. Results A total of 656 319 participants including 150 638 cases with metabolic syndrome were involved in thes 38 articles. A U-shaped relationship between sleep duration and metabolic syndrome was noticed. For short and long sleep duration, the OR=1.11 (95%CI:1.07-1.16) and 1.10 (95%CI:1.03-1.18), respectively. Subgroup analyses on cross-sectional studies revealed that factors as men, aged under 60 years, being Asians or Caucasians would increase the risk of metabolic syndrome by 6%, 14%, 9%, and 24%, respectively for those with short sleep duration. Factors as aged 60 years and above, being black and with long sleep duration, would increase the risks of metabolic syndrome by 13% and 19%, respectively in women. In subgroup analyses on cohort studies, positive correlation between short sleep duration and metabolic syndrome was observed in both Asian (RR=1.10, 95%CI:1.07-1.13) and in Caucasians (RR=1.56, 95%CI:1.08-2.26) populations. Conclusions Results of this study revealed an association between metabolic syndrome and the duration of sleep. We understand that sleep is a behavior that can be changed step by step, through adequate intervention programs, to reduce the risk of metabolic syndrome which has become an important public health issue.
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