文章摘要
唐金陵.临床研究:为什么一定要学好基础[J].中华流行病学杂志,2020,41(12):2160-2162
临床研究:为什么一定要学好基础
Clinical research: why we must mater the essentials
收稿日期:2020-09-30  出版日期:2020-12-25
DOI:10.3760/cma.j.cn112338-20200930-01216
中文关键词: 临床研究;临床流行病学;研究设计
英文关键词: Clinical research;Clinical epidemiology;Study design
基金项目:
作者单位E-mail
唐金陵 广州市妇女儿童医疗中心 510623 jltang@cuhk.edu.hk 
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中文摘要:
      学习临床研究方法,一定要学好基础。所谓基础,就是那些让一个学科之所以成为这个学科的东西,那些万变不离其宗的东西,那些一旦不存在了整个学科就会塌陷的东西。首先,基础是最持久最可靠的东西;其次,基础解决的是最重要的问题;第三,基础是使用频率最高的东西;第四,基础是懂得如何灵活运用的前提。流行病学是临床研究的方法论,其基础不外乎八个字:因果关系、控制偏倚。基础的东西往往有深刻的理论背景,经常是哲学思辨,很抽象很晦涩,是最难琢磨透彻和熟悉掌握的东西,需要用多种方法来揣摩和体悟,最终才会由掌握而诚服。
英文摘要:
      Learning clinical research methods, we must master the essentials. Essentials are the theories, principles and methods that make a discipline a unique discipline, without which the discipline will no more exist. Essentials are those things that are long-lasting and reliable, those that address the most important issues, those that are most frequently used in practice, and those that normally should not be compromised. The core underlying theories of epidemiological research are causation and errors control. The essentials often have profound theoretical underpinnings and difficult to grasp. We will truly believe the theories and observe the principles only when we have truly grasped them.
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