| 葛文鑫,谭伟良,滕皓玥,沈蕙,韩迪,肖月,尹洁云,胡佳.苏州市儿童BMI-Z变化轨迹与青春晚期血压偏高的关联研究[J].中华流行病学杂志,2021,42(10):1809-1816 |
| 苏州市儿童BMI-Z变化轨迹与青春晚期血压偏高的关联研究 |
| Trajectories of body mass index Z-score and risk of high blood pressure in late adolescence in Suzhou children |
| 收稿日期:2020-11-30 出版日期:2021-10-23 |
| DOI：10.3760/cma.j.cn112338-20201130-01365 |
| 中文关键词: 体质指数 血压偏高 肥胖 |
| 英文关键词: BMI High blood pressure Obesity |
| 基金项目:国家自然基金青年基金—青年项目（NSFC81602911）；苏州市科技发展计划（民生科技）（SYS2019115） |
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| 中文摘要: |
| 目的 探讨年龄和性别标准化BMI-Z值（BMI-Z）轨迹与青春晚期（16~18岁）血压偏高的关系。方法 基于苏州市儿童和青少年健康监测项目（HPPCA）2012-2019年的数据，以2019年的监测数据为结局，将末次监测年龄为16~18岁且总监测次数≥4的11 812名儿童青少年纳入研究。运用潜变量生长混合模型分析不同性别儿童成长过程中的BMI动态变化（BMI-Z变化轨迹），采用多因素logistic回归分析BMI动态变化与青春晚期血压偏高的关系。结果 在男、女生中各确定了6条BMI-Z变化轨迹，分别为较瘦组、略瘦组、标准组、下降组、超重组和肥胖组。与标准组相比，男生肥胖组在青春晚期发生血压偏高的风险增加94.0%（OR=1.94，95%CI：1.43~2.63），而女生肥胖组则增加107.0%（OR=2.07，95%CI：1.33~3.22）。男女生中下降组与青春晚期血压偏高发病均没有显著关联。结论 儿童持续性肥胖会增加青春晚期罹患血压偏高的风险；若对肥胖儿童及时采取干预措施，使其在青春晚期恢复正常体重，或许能降低血压偏高的风险。 |
| 英文摘要: |
| Objective To identify age and gender standardized body mass index among children and adolescents and explore their associations with high blood pressure (HBP) in late adolescence. Methods The current study was based on the Health Promotion Program for Children and Adolescents, school-based surveillance successively conducted from 2012 to 2019 in Suzhou, China. A total of 11 812 children and adolescents aged 16-18 years, who had ≥ 4 examination records during 2012-2018 and were also involved in a surveillance program in 2019, were included. Latent class growth mixture modeling was used to identify the BMI-Z trajectories in different genders, and multivariate logistic regression was used to analyze the associations between different BMI-Z trajectories and risk of HBP in late adolescence. Results Six distinct BMI-Z trajectories were determined for both genders:thin, slightly thin,standard, declining, overweight, and obese. Compared with the regular group, the obesity group had 94.0% (OR=1.94, 95%CI:1.43-2.63) and 107.0% (OR=2.07, 95%CI:1.33-3.22) increased risk of developing HBP in late adolescence in boys and girls, respectively. However, a neutral association was found between the descending group and HBP in late adolescence. Conclusions Persistent obesity in children may increase the risk of HBP in their late adolescence. If an obese child restores normal weight before late adolescence, the risk of HBP may reduce. |
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