文章摘要
李自慧,赵琦,龚德光,孙烨祥,沈鹏,林鸿波,何纳.宁波市鄞州区2012-2020年HIV感染者确证后住院率及影响因素分析[J].中华流行病学杂志,2022,43(4):541-547
宁波市鄞州区2012-2020年HIV感染者确证后住院率及影响因素分析
Rates and influencing factors of hospitalization after diagnosis among HIV infection cases in Yinzhou district of Ningbo, 2012-2020
收稿日期:2021-07-19  出版日期:2022-04-16
DOI:10.3760/cma.j.cn112338-20210719-00564
中文关键词: 艾滋病病毒|真实世界|住院率|影响因素
英文关键词: HIV|Real-world data|Hospitalization rate|Influencing factors
基金项目:上海市卫生健康委重点学科建设(GWV-10.1-XK16);宁波市鄞州区科技局科技计划(2017-59-45)
作者单位E-mail
李自慧 复旦大学公共卫生学院流行病学教研室/公共卫生安全教育部重点实验室, 上海 200032  
赵琦 复旦大学公共卫生学院流行病学教研室/公共卫生安全教育部重点实验室, 上海 200032  
龚德光 宁波市鄞州区疾病预防控制中心数据中心, 宁波 315100  
孙烨祥 宁波市鄞州区疾病预防控制中心数据中心, 宁波 315100  
沈鹏 宁波市鄞州区疾病预防控制中心数据中心, 宁波 315100 58757193@qq.com 
林鸿波 宁波市鄞州区卫生健康局, 宁波 315100 lin673160@163.com 
何纳 复旦大学公共卫生学院流行病学教研室/公共卫生安全教育部重点实验室, 上海 200032
复旦大学义乌研究院, 义乌 322001 
nhe@shmu.edu.cn 
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中文摘要:
      目的 分析基于真实世界数据的HIV感染者确证后住院率及影响因素,为艾滋病防控和管理提供依据。方法 基于艾滋病综合防治信息系统和宁波市鄞州区健康大数据平台的回顾性队列研究,收集2012-2020年鄞州区确证HIV感染者病例报告卡、随访管理、抗病毒治疗和住院记录等资料,分析HIV感染者的住院率、住院人次数、住院疾病并用logistic回归模型分析住院的影响因素。结果 在鄞州区2012-2020年确证的763例HIV感染者中,总住院率和总住院人次数分别为6.95%(53/763)和2.59人次/100人年。<30、30~、45~、≥60岁年龄组HIV感染者住院率分别为3.16%(10/316)、6.07%(15/247)、7.86%(11/140)、28.33%(17/60),住院人次数分别为0.81、1.59、4.05、17.40人次/100人年。logistic多因素回归分析结果显示,年龄≥60岁年龄组与HIV感染者有住院史呈显著相关(аOR=14.44,95%CI:3.57~58.46)。艾滋病及相关疾病、心脑血管疾病和代谢异常、其他疾病导致的住院率分别为1.83%(14/763)、1.05%(8/763)、3.93%(30/763)。结论 在抗病毒治疗策略下,鄞州区HIV感染者的住院负担重点人群与普通人群相似,仍然是≥60岁年龄组为主,艾滋病及相关疾病导致的住院比例较少,HIV感染者的总体住院负担增加不明显。
英文摘要:
      Objective To understand the hospitalization rates and influencing factors after diagnosis among HIV infection cases, based on real-world data in Yinzhou district of Ningbo.Methods A retrospective cohort study was conducted based on the databases of National AIDS Comprehensive Response Information Management System and Yinzhou Health Information Platform. The information about the following-up results, antiviral treatment data, electronic records of inpatient of the HIV cases reported during 2012-2020 were collected to analyze the rates, causes and influencing factors of hospitalization. Results Among the 763 HIV infection cases reported in Yinzhou from 2012 to 2020, the hospitalization rate was 6.95% (53/763), and the number of inpatient was 2.59 per 100 person years. The hospitalization rate and the number of hospitalization per 100 person years in HIV infection cases were 3.16% (10/316) and 0.81 in those aged <30 years, 6.07% (15/247) and 1.59 in those aged >30 years, 7.86% (11/140) and 4.05 in those aged >45 years and 28.33% (17/60) and 17.40 in those aged ≥ 60 years respectively. Logistic multivariate regression analysis indicated that being aged ≥ 60 years was the influencing factor for hospitalizations in HIV infection cases (аOR=14.44, 95%CI:3.57-58.46). The hospitalization rates due to AIDS related diseases, cardiovascular diseases and metabolic diseases, and other diseases were 1.83% (14/763), 1.05% (8/763), and 3.93% (30/763), respectively. Conclusions The hospitalization burden due to HIV infection was still mainly caused by those aged ≥ 60 years in Yinzhou, similar to that in general population and less proportion of hospitalizations were due to AIDS related diseases. The overall increase of hospitalizations due to AIDS was not obvious in Yinzhou.
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