| 付亚群,赵婧雨,韩沛恩,杨莉,任涛,詹思延,李立明.新型冠状病毒肺炎非药物干预防控措施经济学评价研究进展[J].中华流行病学杂志,2022,43(7):1030-1037 |
| 新型冠状病毒肺炎非药物干预防控措施经济学评价研究进展 |
| Progress in research of economic evaluation of non-pharmaceutical interventions for COVID-19 prevention and control |
| 收稿日期:2022-02-18 出版日期:2022-07-15 |
| DOI：10.3760/cma.j.cn112338-20220218-00129 |
| 中文关键词: 新型冠状病毒肺炎 疾病负担 非药物干预 经济学评价 |
| 英文关键词: COVID-19 Disease burden Non-pharmaceutical intervention Economic evaluation |
| 基金项目:国家自然科学基金(72174010);北京自然科学基金专项(M22033);首都卫生发展科研专项(2021-1G-4091) |
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| 中文摘要: |
| 目的 了解国内外新型冠状病毒肺炎非药物干预（non-pharmaceutical interventions，NPIs）措施的经济评价研究进展，为开展基于中国真实世界证据的NPIs措施经济学评价提供参考。方法 对中英文数据库2020年1月至2021年12月的文献进行检索，纳入NPIs措施以及不同NPIs措施组合的经济学评价文献，并对相关文献进行叙述性整合。结果 本研究共纳入30篇中英文文献，其中以核酸合并抗原检测/筛查类策略为主的研究7篇，以个人防护类策略为主的研究6篇，个人防护、保持社交隔离、核酸检测、抗原检测/筛查、社区大规模筛查、症状筛查、密切接触者（密接）追踪、隔离组合策略研究12篇，封锁等抑制策略为主的研究5篇。研究发现个人防护、社交距离和筛查-密接追踪-隔离具有成本效果/效用/效益，但不同的组合方式会导致不同结果，此外，封锁成本较高会带来较重的经济负担。结论 除封锁外的NPIs措施大多具有成本效果，不同情境下不同程度NPIs措施组合的成本效果需要再评估。亟需开展基于我国真实世界的NPIs措施组合以及NPIs措施与疫苗、药物等其他干预组合的经济学评价研究。 |
| 英文摘要: |
| Objective To understand the research progresses of economic evaluation of non-pharmaceutical interventions (NPIs) both at home and abroad, and provide reference for economic evaluation of NPIs using real-world data in China. Methods The literature retrieval was conducted by searching Chinese and English databases to indude papers about economic evaluation of NPIs and integrated NPIs published from January, 2020 to December, 2021, and the results were analyzed comprehensively. Results A total of 30 Chinese and English literatures about economic evaluation of NPIs for COVID-19 prevention and control were included; including 7 papers about nucleic acid and testing and screening, 6 papers about individual prevention and protection measures, 12 papers about integrated implementation of individual prevention and protection, social distancing, nucleic acid or antigen testing, community screening and symptom screening, as well as close contact tracing and isolation/quarantine, and 5 papers about contain strategies, such as lockdown. This study found that personal protection, social distancing, and testing-tracing-isolation measures were cost-effective; however, different combinations of NPIs might lead to different results. Moreover, the cost of lockdown was high, which might cause huge economic burden. Conclusions Most NPIs are cost-effective except lockdown, while the cost-effectiveness of the integrations of NPIs at different levels and in different scenarios needs to be further evaluated. It is necessary to carry out economic evaluation of integrated NPIs and the combination of NPIs with other interventions, such as vaccination and medication, based on real-world settings in China. |
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