| 郑英杰,胡安群,陆国平,李意杰,董遥,王凯琳.儿童不明原因急性肝炎事件[J].中华流行病学杂志,2022,43(8):1326-1332 |
| 儿童不明原因急性肝炎事件 |
| The event of acute hepatitis of unknown etiology in children |
| 收稿日期:2022-05-04 出版日期:2022-08-13 |
| DOI：10.3760/cma.j.cn112338-20220504-00376 |
| 中文关键词: 肝炎 儿童 公共卫生 |
| 英文关键词: Hepatitis Children Public health |
| 基金项目:国家重点研发计划（2021YFC2701800，2021YFC2701801）；国家自然科学基金（82173582，81773490） |
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| 中文摘要: |
| 近来，全球不明原因急性肝炎（AHUE）儿童病例数正在快速增加，已涉及26个国家（病例数超过396例），全球公共卫生行动（监测、健康警示、研究等）正在实施中。AHUE主要影响免疫功能健全的儿童，具有典型的急性肝炎表现，可出现重症化且需要肝移植。目前系统的研究仍然较少，其危险因素未明，病因有待于确立，临床特征及发病机制有待于阐明，加强AHUE病例的监测及研究迫在眉睫。 |
| 英文摘要: |
| Recently, the cases of acute hepatitis of unknown etiology (AHUE) in children worldwide have been increasing continuously and rapidly, involving more than 396 cases in 26 countries, and global public health actions, including surveillance, health alerts, research, are being implemented. AHUE mainly affects immunocompetent children with typical acute hepatitis, which can be severe and require liver transplantation. There are few systematic studies at present; the risk factors are unknown, the etiology remains to be established, and the clinical features and pathogenesis remain elucidated. It is urgent to strengthen the monitoring and research of AHUE cases. |
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