文章摘要
宁宁,蔡于茂,翁榕星,王洪琳,文立章,张春来,叶健滨,陈祥生.性病相关门诊无症状就诊者生殖道沙眼衣原体感染现状及影响因素分析[J].中华流行病学杂志,2022,43(9):1436-1440
性病相关门诊无症状就诊者生殖道沙眼衣原体感染现状及影响因素分析
Chlamydia trachomatis infection and its associated factors among asymptomatic outpatients attending sexually transmitted disease-related clinics
收稿日期:2021-10-15  出版日期:2022-09-09
DOI:10.3760/cma.j.cn112338-20211015-00796
中文关键词: 性传播疾病;生殖道沙眼衣原体;无症状就诊者;影响因素
英文关键词: Sexually transmitted diseases;Genital chlamydia trachomatis infection;Asymptomatic outpatients;Associated factors
基金项目:深圳市"医疗卫生三名工程"(SZSM201611077)
作者单位E-mail
宁宁 深圳市慢性病防治中心性病麻风病防控科, 深圳 518020  
蔡于茂 深圳市慢性病防治中心性病麻风病防控科, 深圳 518020 64165469@qq.com 
翁榕星 深圳市慢性病防治中心性病麻风病防控科, 深圳 518020  
王洪琳 深圳市慢性病防治中心性病麻风病防控科, 深圳 518020  
文立章 深圳市慢性病防治中心性病麻风病防控科, 深圳 518020  
张春来 深圳市慢性病防治中心性病麻风病防控科, 深圳 518020  
叶健滨 深圳市慢性病防治中心性病麻风病防控科, 深圳 518020  
陈祥生 中国疾病预防控制中心性病控制中心, 南京 210042  
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中文摘要:
      目的 了解深圳市STD相关门诊无症状就诊者生殖道沙眼衣原体(CT)感染现状及影响因素,为制定干预措施提供参考依据。方法 采用横断面调查研究方法,于2018年4月15日至5月16日在深圳市南山区、罗湖区、宝安区、龙岗区、盐田区、龙华区的22家医疗机构招募STD相关门诊就诊者,完成知情同意后,收集其社会人口学相关信息并采集尿液标本进行CT核酸检测,采用logistic回归分析CT感染的影响因素。结果 无症状就诊者CT感染率为7.16%(250/3 492)。单身(aOR=2.29,95%CI:1.65~3.16)、外地户籍(aOR=1.49,95%CI:1.04~2.13)、最近1年未检测CT(aOR=2.04,95%CI:1.03~4.05)是无症状就诊者CT感染的危险因素。外地户籍中,大专及以下文化程度占89.25%(2 176/2 438),年龄≤30岁占51.29%(1 255/2 447),≤30岁者感染CT的风险是>30岁者的1.73(95%CI:1.28~2.34)倍。结论 深圳市STD相关门诊无症状就诊者CT感染率较高,应针对性活跃年龄段、单身、文化程度较低、最近1年未检测CT的STD相关门诊就诊者开展CT常规筛查,提高重点人群对CT基本知识及不良结局的知晓率,预防不良结局的发生。
英文摘要:
      Objective To understand the prevalence of Chlamydia trachomatis (CT) infection and its associated factors among asymptomatic outpatients attending sexually transmitted disease (STD)-related clinics in Shenzhen and provide evidence for development of future interventions.Methods From April 15 to May 16,2018,a cross-sectional study was conducted and patients attending STD-related Clinics were recruited from 22 medical institutions in Nanshan,Luohu,Bao'an,Longgang,Yantian,and Longhua districts of Shenzhen.After the informed consent from each participant was obtained,social-demographic information was collected through a structured questionnaire and urine samples were collected for CT nucleic acid detection.In addition,logistic regression was used to explore associated factors of CT infection.Results In asymptomatic outpatients,the prevalence of CT infection was 7.16%(250/3 492).Being single (aOR=2.29,95%CI:1.65-3.16),without registered Shenzhen residency (aOR=1.49,95%CI:1.04-2.13),and without previous CT testing in the past year (aOR=2.04,95%CI:1.03-4.05) were the risk factors of CT infection in asymptomatic outpatients.Among participants without registered Shenzhen residency,89.25%(2 176/2 438) were college-degree or below,and 51.29%(1 255/2 447) were aged ≤ 30 years,and the risk of CT infection among those ≤ 30 years old was 1.73 times higher than those>30 years old (95%CI:1.28-2.34).Conclusions The prevalence of CT infection was high among asymptomatic outpatients attending STD-related clinics in Shenzhen.Routine CT screening should be carried out for this population,especially for those with sexually active age,being single,with low educational level,and without previous CT testing in the past year.Also,raising their awareness of knowledge and adverse outcomes of CT infection should be considered to promote routine CT screening and timely treatment.
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