| 张祖样,马婧,马艳玲,宋丽军,肖民扬,李佑芳,王晓雯,王珏,牛瑾,汤后林,罗红兵.云南省男男性行为者HIV暴露前预防用药意愿及相关因素分析[J].中华流行病学杂志,2023,44(1):145-150 |
| 云南省男男性行为者HIV暴露前预防用药意愿及相关因素分析 |
| Willingness of pre-exposure prophylaxis use to prevent HIV infection and related factors in men who have sex with men in Yunnan Province |
| 收稿日期:2022-07-12 出版日期:2023-01-14 |
| DOI：10.3760/cma.j.cn112338-20220712-00623 |
| 中文关键词: 男男性行为者 暴露前预防 意愿 相关因素 |
| 英文关键词: Men who have sex with men Pre-exposure prophylaxis Willingness Related factors |
| 基金项目:国家科技重大专项（2018ZX10715006-006） |
| 作者 | 单位 | E-mail | | 张祖样 | 云南省疾病预防控制中心, 昆明 650000 | | | 马婧 | 云南省疾病预防控制中心, 昆明 650000 | | | 马艳玲 | 云南省疾病预防控制中心, 昆明 650000 | | | 宋丽军 | 云南省疾病预防控制中心, 昆明 650000 | | | 肖民扬 | 云南省疾病预防控制中心, 昆明 650000 | | | 李佑芳 | 云南省疾病预防控制中心, 昆明 650000 | | | 王晓雯 | 云南省疾病预防控制中心, 昆明 650000 | | | 王珏 | 云南省疾病预防控制中心, 昆明 650000 | | | 牛瑾 | 云南省疾病预防控制中心, 昆明 650000 | | | 汤后林 | 中国疾病预防控制中心性病艾滋病预防控制中心, 北京 102206 | tanghl@chinaaids.cn | | 罗红兵 | 云南省疾病预防控制中心, 昆明 650000 | 540122323@qq.com |
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| 中文摘要: |
| 目的 分析云南省男男性行为者HIV暴露前预防（PrEP）用药意愿及影响因素。方法 采用横断面研究设计，通过滚雪球抽样方法在2021年4-6月云南省14个城市（自治州）开展调查。国家级哨点样本量为400人，省级哨点样本量为100人。采用logistic回归分析PrEP用药意愿的相关因素。使用SPSS 22.0软件进行统计学分析。结果 共调查MSM 2 450人，听说过PrEP的比例为68.5%（1 677/2 449），愿意PrEP用药的比例为56.7%（1 343/2 368），愿意自费PrEP用药的比例为30.6%（724/2 368），愿意免费PrEP用药的比例为56.2%（1 330/2 367）。多因素logistic分析结果显示，PrEP用药意愿低的相关因素包括40~和≥50岁（aOR=2.49和aOR=4.48）、汉族（aOR=1.47）、外省户籍（aOR=1.64）、高中/中专（aOR=1.96）与大专及以上文化程度（aOR=3.49）、样本来源分别为浴池/桑拿（aOR=3.53）、网络招募（aOR=2.53）和自愿咨询与检测（aOR=1.42）、本地居住时间3~和7~12个月（aOR=0.18和aOR=0.25）、调查现场分类为二类与三类地区（aOR=3.63和aOR=1.71）、最近1周未发生同性肛交（aOR=2.60）和未发生商业性同性性行为（aOR=13.32）、自我感知HIV感染风险较高者（aOR=0.50）。结论MSM愿意PrEP用药的比例超过一半，PrEP宣传推广工作应重点关注PrEP用药意愿低的MSM，尤其是来自经济较落后地区、年龄较大、汉族、外省户籍、本地居住时间较短和自我感知HIV感染风险较低的MSM。 |
| 英文摘要: |
| Objective To understand the willingness of pre-exposure prophylaxis (PrEP) use to prevent HIV infection and related factors in men who have sex with men (MSM) in Yunnan Province. Methods Cross-sectional study method and snowball sampling method was used to carry out the survey in 14 cities (autonomous prefectures) in Yunnan from April to June 2021. According to national sentinel surveillance program, the sample size was 400 at national sentinel sites and 100 at provincial sentinel sites. The related factors of PrEP use willingness were analyzed by multiple logistic regressions with software SPSS 22.0. Results A total of 2 450 questionnaires were completed, the rate of having heard of PrEP was 68.5% (1 677/2 449), the willingness rate of PrEP use was 56.7% (1 343/2 368), the willing rate of PrEP use at their own expense was 30.6% (724/2 368), and the willingness rate of free PrEP use was 56.2% (1 330/2 367). The of multivariate logistic analysis results showed that related factors of low willingness to use PrEP included aged 40-49 years and 50 years or above (aOR=2.49 and aOR=4.48), Han ethnic group (aOR=1.47), residence in other provinces (aOR=1.64), education level of senior high school (aOR=1.96) and college or above (aOR=3.49), sample source of bath house (aOR=3.53), online recruiting (aOR=2.53) and voluntary counseling and testing (aOR=1.42), local living time for 3-6 months and 7-12 months (aOR=0.18 and aOR=0.25) ,class 2 and 3 of survey areas (aOR=3.63 and aOR=1.71), having no anal sex with men in the past week (aOR=2.60), having no commercial homosexual behavior in the past six months (aOR=13.32) and self-perceived higer risk for HIV infection (aOR=0.50). Conclusions There was more than half of MSM with willingness to use PrEP. The health education to promote PrEP use should be strengthen in MSM who had low willingness to use PrEP from underdeveloped areas, in Han ethnic group, with older age, from other provinces, with shorter local living time and self-perceived low risk for HIV infection. |
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