| 关明玥,秦倩倩,金怡晨,陈方方,蔡畅,汤后林.2013-2021年我国报告60岁及以上HIV感染者死亡情况及变化趋势分析[J].中华流行病学杂志,2023,44(11):1679-1685 |
| 2013-2021年我国报告60岁及以上HIV感染者死亡情况及变化趋势分析 |
| Analysis on mortality and change trend of HIV-infected patients aged 60 years and older reported in China, 2013-2021 |
| 收稿日期:2023-04-23 出版日期:2023-11-17 |
| DOI：10.3760/cma.j.cn112338-20230423-00262 |
| 中文关键词: 艾滋病病毒/艾滋病 老年 死亡密度 变化趋势 |
| 英文关键词: HIV/AIDS Elderly Mortality density Change trend |
| 基金项目:国家自然科学基金（71874168） |
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| 中文摘要: |
| 目的 分析2013-2021年我国≥60岁HIV感染者的死亡情况及变化趋势。方法 从中国疾病预防控制信息系统收集报告年龄≥60岁的HIV感染者，计算死亡密度，并利用SAS 9.4软件中的Proc traj过程拟合轨迹分析模型，探索不同地区、性别和年龄组合下艾滋病相关死亡密度和非艾滋病相关死亡密度的发展轨迹。结果 2013-2021年我国累计报告≥60岁HIV感染者244 770例，其中艾滋病相关死亡40 079例，非艾滋病相关死亡50 245例。艾滋病相关死亡密度为6.32/100人年，非艾滋病相关死亡密度为7.92/100人年，两者均呈下降趋势，且男性死亡密度均高于女性。艾滋病相关死亡密度变化趋势存在2种发展轨迹：较低死亡密度组占80.95%，呈缓慢降低趋势；较高死亡密度组占19.05%，呈3次曲线发展趋势。非艾滋病相关死亡密度变化趋势存在3种发展轨迹：较低死亡密度组占59.52%，中等死亡密度组占28.57%，这两组总体发展趋势平缓；较高死亡密度组占11.91%，呈3次曲线发展趋势。结论 我国≥60岁HIV感染者死亡情况仍不容乐观，需加强早发现、早诊断和早治疗等各种措施以进一步降低艾滋病相关死亡密度，同时应关注老年人非艾滋病相关死亡的情况，采取综合性的干预措施。不同地区和人群需结合自身特点有针对性地开展艾滋病防控工作。 |
| 英文摘要: |
| Objective To analyze the basic characteristics and change trend of mortality in HIV-infected patients aged ≥ 60 years in China from 2013 to 2021. Methods The data of HIV-infected patients aged ≥ 60 years at diagnosis were collected from China Information System for Disease Control and Prevention to calculate the mortality density. The trajectory model was fitted using the Proc traj process in software SAS 9.4 to explore trajectory of AIDS-related mortality density and non-AIDS-related mortality density under different combinations of region, gender and age. Results Between 2013 and 2021, a total of 244 770 HIV-infected patients were reported with 40 079 AIDS-related deaths and 50 245 non-AIDS-related deaths. The AIDS-related mortality density was 6.32 per 100 person-years, and the non-AIDS-related mortality density was 7.92 per 100 person-years, both of which showed decreasing trends over the years, and the mortality density in men was higher than that in women. Two developmental trajectories could be categorized for different trends of AIDS-related mortality density:the lower mortality density group accounted for 80.95% and showed a slow decreasing trend; the higher mortality density group accounted for 19.05% and showed a three-curve developmental trend. There were three developmental trajectories of non-AIDS-related mortality density trends:the lower mortality density group accounted for 59.52% and the medium mortality density group accounted for 28.57%, with a flat overall trend in these two groups; the higher mortality density group accounted for 11.91% with a three-curve trend. Conclusions The mortality in HIV-infected patients aged ≥ 60 years in China is still high. Further attention should be paid to the early detection, diagnosis and treatment of HIV infection to effectively reduce the density of AIDS-related deaths. At the same time, attention should be paid to non-AIDS-related deaths in the elderly, and comprehensive interventions should be taken. It is necessary to conduct targeted HIV/AIDS prevention and control based on actual situation in different areas and populations |
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