| 徐越,胡秀静,周晓燕,陈赫妮,张雪海,李娜,俞敏.浙江省30岁及以上居民主动吸烟对癌症死亡的归因疾病负担分析[J].中华流行病学杂志,2025,46(8):1360-1365 |
| 浙江省30岁及以上居民主动吸烟对癌症死亡的归因疾病负担分析 |
| Attributable disease burden of active smoking on cancer mortality among residents aged 30 and above in Zhejiang Province |
| 收稿日期:2024-12-09 出版日期:2025-08-21 |
| DOI:10.3760/cma.j.cn112338-20241209-00783 |
| 中文关键词: 吸烟 癌症 人群归因分值 寿命损失年 |
| 英文关键词: Smoking Cancer Population attributable fraction Years of life lost |
| 基金项目:四大慢病重大专项(2023ZD0510104,2023ZD0510100) |
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| 中文摘要: |
| 目的 分析主动吸烟对浙江省≥30岁居民癌症死亡造成的疾病负担。方法 采用全球疾病负担研究比较风险评估研究方法,利用2020年浙江省成人烟草使用监测数据和死因监测数据,建立线性回归模型,估算主动吸烟导致浙江省≥30岁居民癌症死亡的人群归因分值(PAF)、早死寿命损失年(YLL)和潜在工作损失年(WPYLL)。结果 2020年浙江省监测地区≥30岁居民癌症死亡81 536名,其中归因于主动吸烟的死亡24 518名(PAF为30.07%,归因死亡率为55.04/10万);YLL为553 078人年,标化YLL率为12.40‰,WPYLL为56 606人年;在各癌种中,喉癌归因于吸烟的PAF最高(44.75%),而肺癌的归因死亡人数和寿命损失最大,其标化YLL率达4.65‰。结论 主动吸烟是浙江省癌症死亡的重要危险因素,其中肺癌的疾病负担最为突出;亟需加快推进控烟立法,加强针对性干预和癌症早期筛查,以降低人群吸烟相关癌症的疾病负担。 |
| 英文摘要: |
| Objective To analyze the attributable burden of active smoking on the deaths of cancer in inhabitants aged 30 years and above in Zhejiang Province. Methods Comparative risk assessment approach in the Global Burden of Disease Study was used with the data from Zhejiang Adult Tobacco Surveillance System and Death Monitoring Surveillance System in 2020, and population attributable fraction (PAF), years of life lost (YLL), work of potential years of life lost (WPYLL) attributed to smoking on the deaths of cancer in inhabitants aged 30 years and above in Zhejiang Province were calculated with a linear regression model. Results In 2020, there were 81 536 cancer deaths aged 30 years and above in the surveillance areas of Zhejiang Province, of which 24 518 were attributed to active smoking (PAF: 30.07%, attributable mortality rate: 55.04/100 000). The YLL was 553 078 person-years, with a standardized YLL rate of 12.40‰, and the WPYLL was 56 606 person-years. Among various cancer types, laryngeal cancer had the highest smoking-attributable PAF (44.75%), while lung cancer accounted for the most significant number of attributable deaths and life loss, with an age-standardized YLL rate of 4.65‰. Conclusions Active smoking is a significant risk factor for cancer mortality in Zhejiang Province, with lung cancer posing the most significant disease burden. It is urgent to advance tobacco control legislation, strengthen targeted interventions, and promote early cancer screening to reduce the disease burden associated with smoking-related cancers effectively. |
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