| 范文凭,于昕辉,齐金蕾,由金玲,刘韫宁,刘江美,王黎君.2010-2021年中国心血管疾病死亡负担变化趋势分析[J].中华流行病学杂志,2025,46(9):1562-1569 |
| 2010-2021年中国心血管疾病死亡负担变化趋势分析 |
| Analysis of the trend changes in the burden of cardiovascular disease mortality in China from 2010 to 2021 |
| 收稿日期:2025-01-09 出版日期:2025-09-12 |
| DOI：10.3760/cma.j.cn112338-20250109-00024 |
| 中文关键词: 心血管疾病 死亡 伤残调整寿命年 疾病负担 |
| 英文关键词: Cardiovascular disease Death Disability-adjusted life year Burden of disease |
| 基金项目:四大慢病重大专项（2023ZD0503500） |
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| 中文摘要: |
| 目的 分析2010-2021年中国心血管疾病死亡负担现状及变化趋势。方法 从2021年全球疾病负担研究（GBD2021）数据库中提取心血管疾病死亡和伤残调整寿命年（DALY）相关数据。采用GBD2021估计的2021年世界标准人口计算标化死亡率和标化DALY率。使用Joinpoint 5.2.0软件计算2010-2021年我国心血管疾病的死亡率、标化死亡率、DALY率和标化DALY率的年变化百分比（APC）、平均年变化百分比（AAPC）及其95%CI。结果 2021年我国心血管疾病死亡率为357.44/10万，标化死亡率为280.11/10万；DALY率为7 043.33/10万，标化DALY率为5 120.06/10万。2010-2021年我国心血管疾病死亡率和DALY率呈上升趋势（AAPC分别为1.58%和0.83%，均P<0.05），标化死亡率和标化DALY率呈下降趋势（AAPC分别为-2.13%和-2.02%，均P<0.05）。男性心血管疾病死亡负担（死亡率为392.80/10万，DALY率为8 156.19/10万）高于女性（死亡率为320.38/10万，DALY率为5 876.87/10万）。随着年龄的增长，我国心血管疾病死亡负担呈先减少后增加的趋势。中国在二十国集团成员国中心血管疾病死亡负担排名较高。结论 中国心血管疾病死亡负担较为严重，2010-2021年心血管疾病死亡率和DALY率呈上升趋势， 且标化死亡率和标化DALY率在二十国集团成员国中排名较高。男性和老年人群心血管疾病死亡负担更加严重，针对男性和老年人群，需要制定更加完善的预防、治疗和康复措施，以降低其死亡和伤残率，减轻疾病负担，提高生活质量。 |
| 英文摘要: |
| Objective To analyze the current status and trend of the mortality burden of cardiovascular disease in China from 2010 to 2021. Methods Data related to cardiovascular disease mortality and disability-adjusted life year (DALY) were extracted from the Global Burden of Disease Study 2021 (GBD2021) database. The age-standardized mortality rate and DALY rate were calculated, using the 2021 world standard population estimated by GBD2021. Joinpoint 5.2.0 software was used to calculate the mortality rate, standardized mortality rate, DALY rate, standardized DALY rate, annual percent change (APC), average annual percent change (AAPC), and 95%CI of cardiovascular disease in China from 2010 to 2021. Results The mortality rate of cardiovascular disease was 357.44/100 000, and the age-standardized mortality rate was 280.11/100 000 in China in 2021. The DALY rate was 7 043.33/100 000, and the age-standardized DALY rate was 5 120.06/100 000. From 2010 to 2021, the mortality rate and DALY rate of cardiovascular disease in China showed an upward trend (AAPC was 1.58% and 0.83%, respectively, both P<0.05), and the standardized mortality rate and standardized DALY rate showed a downward trend (AAPC was -2.13% and -2.02%, respectively, both P<0.05). The mortality burden of cardiovascular disease was higher in males (mortality rate 392.80/100 000, DALY rate 8 156.19/100 000) than in females (mortality rate 320.38/100 000, DALY rate 5 876.87/100 000). With the increase older in age, the mortality burden of cardiovascular disease in China decreased first and then increased. China ranked high in the mortality burden of cardiovascular disease among G20 member countries. Conclusions The death burden of cardiovascular disease is serious in China. The mortality rate and DALY rate of cardiovascular disease in China showed an increasing trend from 2010 to 2021, and the standardized mortality rate and standardized DALY rate of cardiovascular disease ranked high in G20 member countries. The death burden of cardiovascular disease was more serious in men and the elderly. It is necessary to develop more comprehensive prevention, treatment, and rehabilitation measures for men and the elderly to reduce mortality and disability rates, decrease the disease burden, and improve the quality of life. |
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