| 栾桂杰,刘少楠,刘尧,孙靓,孙辉峰,张伟燕.2015-2024年山东省重点人群流感疫苗接种趋势及地区差异分析[J].中华流行病学杂志,2025,46(9):1586-1592 |
| 2015-2024年山东省重点人群流感疫苗接种趋势及地区差异分析 |
| Trend and area specific difference analysis on influenza vaccination coverage in key populations in Shandong Province, 2015-2024 |
| 收稿日期:2025-03-04 出版日期:2025-09-12 |
| DOI：10.3760/cma.j.cn112338-20250304-00129 |
| 中文关键词: 流感疫苗 重点人群 趋势分析 地区差异 |
| 英文关键词: Influenza vaccine Key populations Trend analysis Regional disparities |
| 基金项目:中华预防医学会疫苗与免疫青年人才托举项目（CPMAQT_YM0314）；山东省疾病预防控制中心青年创新基金（QC-202301） |
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| 中文摘要: |
| 目的 分析山东省重点人群流感疫苗的接种趋势变化及地区差异，为流感的人群防控提供参考。方法 收集整理山东省预防接种信息系统中重点人群2015-2024年的流感疫苗接种数据，利用Joinpoint 5.3.0软件计算年变化百分比和平均年变化百分比（AAPC），分析接种率的变化趋势并比较地区差异。结果 2015-2024年山东省医务人员的流感疫苗接种率在0.02%~20.54%（AAPC=63.24%，95%CI：51.37%~100.65%），2015-2020年快速升高（P<0.001），2020-2024年稳步下降（P=0.008）。教师/学生的接种率在1.51%~6.88%（AAPC=12.33%，95%CI：-0.97%~36.27%），2015-2024年单调递增（P=0.070）。≥60岁老年人的接种率在0.03%~11.68%（AAPC=102.65%，95%CI：64.16%~208.69%），2015-2017年快速上升（P<0.001）、2017-2020年稳步上升（P<0.001）、2020-2024年增速放缓（P=0.046）。流感疫苗接种率的时间变化趋势存在地区差异，相较于低国内生产总值（GDP）地区，高GDP和中GDP地区的接种率及增长速度明显更高。结论 2015-2024年山东省重点人群流感疫苗接种率呈上升趋势，≥60岁老年人接种率增速明显，需重点关注提高低GDP地区、教师/学生人群的接种率。 |
| 英文摘要: |
| Objective To analyze the changing trends and area specific differences in influenza vaccination coverage in key populations in Shandong Province and provide evidence for influenza prevention and control. Methods The information about influenza vaccination in Shandong during 2015 to 2024 were collected from the Immunization Information System of Shandong Province, and the annual percentage change and average annual percentage change (AAPC) were calculated by using software Joinpoint 5.3.0. The trend of changes in vaccination coverage was analyzed and area specific differences were compared. Results From 2015 to 2024, the influenza vaccination coverage in medical personnel ranged from 0.02% to 20.54% in Shandong (AAPC=63.24%, 95%CI: 51.37%-100.65%), showing a rapid increase from 2015 to 2020 (P<0.001) and a stead decrease from 2020 to 2024 (P=0.008). The vaccination coverage in teachers and students ranged from 1.51% to 6.88% (AAPC=12.33%, 95%CI: -0.97%-36.27%), with a monotonic increase from 2015 to 2024 (P=0.070). The vaccination coverage in elderly people aged ≥60 years ranged from 0.03% to 11.68% (AAPC=102.65%, 95%CI: 64.16%-208.69%), with a rapid increase from 2015 to 2017 (P<0.001), a steady increase from 2017 to 2020 (P<0.001), and a slower increasee from 2020 to 2024 (P=0.046). There were area speciific differences in the temporal trend of influenza vaccination coverage. Compared with areas with low gross domestic product (GDP), the areas with high and medium GDP had significantly higher vaccination coverage and increase rates.Conclusions The influenza vaccination coverage in key populations showed an upward trend in Shandong from 2015 to 2024, and the vaccination coverage in elderly people aged ≥60 years increased significantly. However, it is important to increase vaccination coverage in areas with low GDP and in teachers and students. |
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