| 郭世龙,韩苗林,张艺玺,程秋云,张帆.海南省中老年人血脂异常现况及影响因素分析[J].中华流行病学杂志,2026,47(3):458-464 |
| 海南省中老年人血脂异常现况及影响因素分析 |
| Analysis on dyslipidemia and influencing factors in middle-aged and elderly people in Hainan Province |
| 收稿日期:2025-06-11 出版日期:2026-03-19 |
| DOI：10.3760/cma.j.cn112338-20250611-00395 |
| 中文关键词: 血脂异常|中心性肥胖|中老年人 |
| 英文关键词: Dyslipidemia|Central obesity|Middle-aged and elderly |
| 基金项目:国家重点研发计划（2017YFC0907104）；国家自然科学基金（81860577）；海南省研究生创新科研课题（Qhys2024-423） |
| 作者 | 单位 | E-mail | | 郭世龙 | 海南医科大学公共卫生学院, 热带转化医学教育部重点实验室, 海口 571199 | | | 韩苗林 | 海南医科大学公共卫生学院, 热带转化医学教育部重点实验室, 海口 571199 | | | 张艺玺 | 海南医科大学公共卫生学院, 热带转化医学教育部重点实验室, 海口 571199 | | | 程秋云 | 海南医科大学公共卫生学院, 热带转化医学教育部重点实验室, 海口 571199 | | | 张帆 | 海南医科大学公共卫生学院, 热带转化医学教育部重点实验室, 海口 571199 | zhangfan@muhn.edu.cn |
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| 中文摘要: |
| 目的 了解海南省中老年人血脂异常流行现况及其影响因素。方法 选取海南省35~74岁常住居民作为研究对象，通过问卷调查收集研究对象基本信息，通过实验室血生化检测获取血脂四项指标，描述血脂异常检出率及分布特征。采用χ2检验、秩和检验和多因素logistic回归模型进行单因素和多因素分析。结果 本研究共纳入5 433人，其中男性2 710人（49.8%），女性2 723人（50.2%），年龄M（Q1，Q3）为47（41，55）岁，血脂异常2 879人（52.9%）。多因素logistic回归分析结果显示，年龄每增长1岁（起始年龄35岁），血脂异常风险增加3.7%（OR=1.037，95%CI：1.029~1.044）；与女性相比，男性血脂异常风险增加48.4%（OR=1.484，95%CI：1.262~1.745）；与非中心性肥胖者相比，中心性肥胖者血脂异常风险增加54.5%（OR=1.545，95%CI：1.365~1.748）；与不吸烟/已戒烟者相比，偶尔吸烟/经常吸烟者血脂异常风险增加24.5%（OR=1.245，95%CI：1.061~1.460）；与身体水分含量正常相比，身体水分含量偏低者血脂异常风险增加56.4%（OR=1.564，95%CI：1.230~1.998），身体水分含量偏高者血脂异常风险减少45.4%（OR=0.546，95%CI：0.381~0.781）。与血糖正常者相比，患有糖尿病者血脂异常风险增加56.8%（OR=1.568，95%CI：1.230~1.998）；与血压正常者相比，患有高血压者血脂异常风险增加47.7%（OR=1.477，95%CI：1.299~1.679）。结论 年龄、性别（男性）、中心性肥胖、身体水分含量偏低、吸烟、糖尿病和高血压是中老年人血脂异常的危险因素，而身体水分含量偏高是保护因素。 |
| 英文摘要: |
| Objective To understand the prevalence of dyslipidemia and the influencing factors in middle-aged and elderly people in Hainan Province. Methods Adult residents aged 35-74 years in Hainan Province were enrolled. Basic information was collected via questionnaires, and four serum lipid parameters were measured by biochemical assays in the laboratory. The detection rate and distribution of dyslipidemia were determined. Univariate and multivariable analyses were performed using χ2 test, the rank-sum test, and multivariable logistic regression. Results A total of 5 433 individuals were included in this study, in whom 2 710 were men (49.8%) and 2 723 were women (50.2%), 2 879 had dyslipidemia (52.9%). The M (Q1, Q3) age of the study participants was 47 (41, 55) years. Multivariate logistic regression analysis revealed that for each 1 year increase of age (with the baseline age of 35 years), the risk for dyslipidaemia increased by 3.7% (OR=1.037, 95%CI: 1.029-1.044). Compared with women, men had a 48.4% (OR=1.484, 95%CI: 1.262-1.745) higher risk for dyslipidaemia. Individuals with central obesity had a 54.5% (OR=1.545, 95%CI: 1.365-1.748) higher risk compared with those without central obesity. Occasional or regular smokers had a 24.5% (OR=1.245, 95%CI: 1.061-1.460) higher risk compared with non-smokers or former smokers. Those with low body water content had a 56.4% (OR=1.564, 95%CI: 1.230-1.998) higher risk, while those with high body water content had a 45.4% (OR=0.546, 95%CI: 0.381-0.781) lower risk compared with individuals with normal hydration status. Additionally, individuals with diabetes or hypertension had a 56.8% (OR=1.568, 95%CI: 1.230-1.998) and 47.7% (OR=1.477, 95%CI: 1.299-1.679) higher risk for dyslipidaemia, respectively, compared with those with normal blood glucose level or blood pressure. Conclusion In middle-aged and elderly adults in Hainan, age, being man, central obesity, low body water content, smoking, diabetes, and hypertension were identified as significant risk factors for dyslipidemia, whereas high body water content was a protective factor. |
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