| 余松林,梁浩材,杨璞娜,胡义德,孙耀华,白银明,张明和,姚楚云.河南移民的食管癌流行病学分析[J].Chinese journal of Epidemiology,1987,8(6):358-362 |
| 河南移民的食管癌流行病学分析 |
| An Epidemiological Analysis of Esophageal Cancer Among Migrants from Henan Province |
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| DOI： |
| KeyWord: 食管癌流行病学 移民 死亡率 营养分析 队列研究 |
| English Key Word: Epidemiology of esophageal cancer Migrants Mortality rates Nutritional analysis Cohort study |
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| Abstract: |
| 在1966~69年间,有5万多人自河南食管癌高发区迁入湖北低发区。经14年观察,移民食管癌年死亡率在40.05~99.58/10万之间,未见明显下降;而本地人的年死亡率在0~22.0/10万人之间,差异非常显著。营养调查表明,各类人群的主食构成比例不同,以原籍居民的营养水平最低,新鲜瓜菜、动物蛋白质和油类的摄入量分别为本地人的1/3、1/6及4/7,移民的营养水平介于二者之间。对30岁以上移民及本地人进行了9年5个月的队列观察,发现食管上皮重度增生的RR=3.02,有配偶死于食管癌者的RR=2.70,有血缘亲属死于食管癌者的RR=1.58。食管部位自觉症状每提高一个等级的RR=1.40,吸烟不是重要因素,饮酒与食管癌死亡无关。 |
| English Abstract: |
| From 1966 to 1969, more than 50,000 migrants from high risk area of esophageal cancer in Henan Province settled in Dachaihu, a low risk area of the disease in Hubei Province. According to death registration in the area over 14 years, the death rates of esophageal cancer are 40.05-99.58 per 100,000 population among migrants with no obvious decline observed and 0-22.0 per 100,000 population among indigenous inhabitants. The difference between the two rates is very significant. Nutritional investigation indicated that constitutional proportion of main cereals consumed by seperate inhabitant group is different from each other, the nutritional condition of people in homeland remains in the lower level, the amounts of green vegetables and fresh melon, animal protein and oil consumed by the people in homeland are about 1/3, 1/6 and 4/7 respectively. In comparison with indigenous inhabitants, the nutritional condition for migrants belongs to a transition type. The results of a cohort study lasted over 9 years and 5 months for people at age of 30 years and over showed that (relative risk) RR=3.02 for heavy proliferation of squamous cells in esophagus, RR=2.70 for history of spouse died of esophageal cancer, RR=1.58 for history of relatives in blood lineage died of the disease, RR=1.40 for one scale increase of subjective symtom in esophageal position, smoking is not a important risk factor for esophageal cance and no relation has been found between alcohol and esophageal cancer. |
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