| 阎永平,王珊珊,徐德忠,周华,陈友绩,王好善,李清甫,贾国法,王庆功,王广文.急性病毒性肝炎的病例对照研究与分型转归研究[J].Chinese journal of Epidemiology,1992,13(1):5-8 |
| 急性病毒性肝炎的病例对照研究与分型转归研究 |
| Risk Factor for Acute Viral Hepatitis: A Case-Control Study |
| Received:August 19, 1990 Revised:November 10, 1990 |
| DOI： |
| KeyWord: 甲型病毒性肝炎 乙型病毒性肝炎 非甲非乙型病毒性肝炎 病例对照研究 多因素分析 |
| English Key Word: Hepatitis A Hepatitis B Non-A, non-B hepatitis Case-control study Multifactorial analysis |
| FundProject: |
| Author Name | Affiliation | | Yan Yongping | Department of Epidemiology, The Fourth Military Medical College, Xian | | 王珊珊 | Department of Epidemiology, The Fourth Military Medical College, Xian | | 徐德忠 | Department of Epidemiology, The Fourth Military Medical College, Xian | | 周华 | Department of Epidemiology, The Fourth Military Medical College, Xian | | 陈友绩 | Department of Epidemiology, The Fourth Military Medical College, Xian | | 王好善 | 解放军第150医院 | | 李清甫 | 解放军第150医院 | | 贾国法 | 解放军第150医院 | | 王庆功 | 解放军第371医院 | | 王广文 | 解放军第371医院 |
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| Abstract: |
| 对两所医院162例急性病毒性肝炎患者进行了血清学分型和流行病学研究,并对发病的一些危险因素按成组和配对方法进行了病例对照研究。结果甲肝为37.0%,乙肝为40.7%,非甲非乙型肝炎为19.8%。经单因素和多因素Logistic回归分析,甲肝发病主要与肝炎接触史(OR=10.56)和不洁饮食史(OR=4.25)有关;乙肝与肝炎接触史(OR=4.30)和家庭成员既往肝炎史(OR=5.66)有关;非甲非乙型肝炎与肝炎接触史(OR=3.82)、输血史(OR=16.67)和既往肝炎史(OR=6.56)有关。甲肝、乙肝和非甲非乙型肝炎的转慢率分别为0%、12.1%和16.7%。 |
| English Abstract: |
| One hundred and sixty-two patients with acute viral hepatitis in two hospitals were studied between Jaunary and December, 1988. The risk factors, epidemiologic features and prognosis of those patients were investigated by case-control and follow-up study. Among the 162 patients, 37.0% were hepatitis A, 40.7%were hepatitis B, and 19.8% were non-A, nonB hepatitis:there were 4 cases of mixed infection and 3 cases of fulminant hepatitis not included in the study. By simple case-control and logistic regression analysis, the patients of hepatitis A more often had history of personal contact with hepatitis cases (OR=10.56) and of ingesting some contaminated foods (OR=4.25); hepatitis B more often had history of personal contact with hapatitis cases in their families or elsewhere (OR=5.66; OR=4.30 respectively), and hepatitis NANB more often had history of previous clinical hepatitis episode (OR=6.56), of personal contact with cases of hepatitis (OR=3.82) and of receiving a blood transfusion(OR=16.67).Among hepatitis A, B and NANB cases, sequelae of chronic hepatitis after acute phase were found in 0%, 12.1% and 16.7% of cases, respectively. |
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