| 肖瑞明,黄丽娟,陈志辉,汪伟业,秦一中.重型病毒性肝炎患者的病死概率监测与临床应用初探[J].Chinese journal of Epidemiology,1993,14(4):204-207 |
| 重型病毒性肝炎患者的病死概率监测与临床应用初探 |
| Evaluation of Surveillance on the Case Fatality Rates in Patients with Severe Hepatitis and of Its Clinical Application |
| Received:October 20, 1992 Revised:February 10, 1993 |
| DOI： |
| KeyWord: 重型肝炎 Logistic回归 概率 |
| English Key Word: Severe hepatitis Logistic regression Case fatality rate |
| FundProject: |
| Author Name | Affiliation | | Xiao Ruiming | Department of Infectious Diseases, Changhai Hospital, The Second Military Medical University, Shanghai 200433 | | 黄丽娟 | 第二军医大学卫生勤务学系统计学教研室 | | 陈志辉 | Department of Infectious Diseases, Changhai Hospital, The Second Military Medical University, Shanghai 200433 | | 汪伟业 | Department of Infectious Diseases, Changhai Hospital, The Second Military Medical University, Shanghai 200433 | | 秦一中 | Department of Infectious Diseases, Changhai Hospital, The Second Military Medical University, Shanghai 200433 |
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| Abstract: |
| 重型肝炎的治疗转归主要取决于患者就诊时病情的发展阶段。采用Logistic回归方法,对201例患者的临床及实验室资料进行历史前瞻性分析,筛选出凝血酶原活动度(Pa)、白球蛋白比值(A/G)、血清胆红素(SB)、肌酐(Cr)、肝性脑病(B)、感染(I)及消化道出血(H)等7个对预后影响最大的变量,组成多元线性回归方程,用来提供患者的病死概率值,借以划分病期,为改进临床科研分组方法、制订治疗方案提供依据。 |
| English Abstract: |
| The prognosis of patients with severe hepatitis is related to the severity of the disease when they are admitted to hospital. We retrospectively analyzed the clinical and laboratory data of 201 cases of severe hepatitis with the method of logistic regression and had obtained 8 independent variables strongly affecting the prognosis to form the multiple regression discriminant equation. The eight independent variables are Pa, A/G, SB, BUN, Cr, hepatic encephalopathy, infection and digestive tract bleeding.We can get the values of case fatality rates from the equation. The degree of severity can be classified with the value. Treatment plans can be drawn out and clinical research grouping can be improved on the basis of the values. |
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