| 段一娟,郑锡文,郑长虹,郗承会,杨忠桔,杨映全,吴运超,李州林,陈钧.云南省瑞丽市静注毒品人群HIV感染者死亡情况调查[J].Chinese journal of Epidemiology,1995,16(2):71-73 |
| 云南省瑞丽市静注毒品人群HIV感染者死亡情况调查 |
| Investigation of Mortality Among HIV-Infected Intravenous Drug Users in Ruili Region of Yunnan Province |
| Received:August 05, 1994 |
| DOI： |
| KeyWord: 人类免疫缺陷病毒 艾滋病 静注吸毒 |
| English Key Word: HIV AIDS IDU |
| FundProject: |
| Author Name | Affiliation | | Duan Yi-juan | Ruili Municipal Sanitary & Anti-Epidemic Station, Yunnan Province, Ruili 678600 | | Zheng Xi-wen | 中国预防医科学院流行病学微生物学研究所 | | Zhen Chang-hong | Ruili Municipal Sanitary & Anti-Epidemic Station, Yunnan Province, Ruili 678600 | | 郗承会 | Ruili Municipal Sanitary & Anti-Epidemic Station, Yunnan Province, Ruili 678600 | | 杨忠桔 | Ruili Municipal Sanitary & Anti-Epidemic Station, Yunnan Province, Ruili 678600 | | 杨映全 | Ruili Municipal Sanitary & Anti-Epidemic Station, Yunnan Province, Ruili 678600 | | 吴运超 | 云南省第一人民医院 | | 李州林 | Ruili Municipal Sanitary & Anti-Epidemic Station, Yunnan Province, Ruili 678600 | | 陈钧 | 中国预防医科学院流行病学微生物学研究所 |
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| Abstract: |
| 采用回顾性前瞻研究对1989年10月~1993年10月瑞丽市静注毒品人群HIV感染者死亡情况进行调查。在观察期内,395名HIV阳性队列中死亡61人,累计死亡率15.4%对照组192名HIV阴性静注毒品队列死亡18人,累计死亡率9.4%,两相比较差异显著(P<0.05),相对危险度(RR)1.6(95%可信区间1.0~2.5)。按死因分类后,两队列死因不明和意外死亡类别差异不显著(P>0.05),且均保持较高的主要为由吸毒过量、殴斗自杀行为所致的意外性死亡率(分别为4.7%、5.8%)。但是,在因病死亡类别,HIV阳性队列死亡率为8.4%,显著高于HIV阴性队列3.1%的水平(P<0.05),RR为2.7(95%可信区间2.1~6.1)。若去除HIV阳性队列中2名AIDS死亡病例后,比较两队列非AIDS性死亡率,HIV阳性队列为13.9%,HIV阴性队列为7.9%,差异显著(P<0.05),RR为1.7(95%可信区间1.0~2.8)。结果表明,瑞丽市的静注毒品者中,HIV阳性人群死于疾病的机会较HIV阴性人群高,其中可能包括部分漏报的AIDS病例,提示今后应加强对基层卫生人员有关AIDS诊断标准的培训。 |
| English Abstract: |
| The investigation of death condition of HIV infected intravenous drug users (IVDU) was conducted with a retrospective cohort study in Ruili city of Yunnan province from 1989-Oct to 1993-Oct, the deaths among 395 HIV+IVDUs add up to 61 and the mortality is 15.4%, which has significant difference compared to the death level of control cohort composed by 192 HIV-IVDUs (add up to 18). The relative risk of death is 1.6 (95% confidence interval 1.0~2.5). After classified by the cause of death, it was found that both maintain high accidence mortality caused mainly by narcotism, violence and suicide. But in death group caused by diseases, the mortality of HIV+IVDU (8.4%) is much higher than HIV-IVDU (3.1%) (95% confidence interval 1.2~6.1). We also compared non -AIDS mortality between HIV+ and HIV-IVDU according to data of HIV/AIDS survellance which showed 2 patients died of AIDS in HIV+ IVDU. The difference is also significant (13.8% in HIV+, but 7.9% in HIV-IVDU) and the relative risk is 1.7 (95% confidence interval 1.0~2.8). The results indicated that the lever of reported AIDS cases were probably lower than that of actual AIDS cases existing. |
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