| 陈春富,陈同慧,贾海燕,郭述苏,薛慎伍,于金萍,尚明谦,曹秉振.Binswanger型白质脑病危险因素的探讨[J].Chinese journal of Epidemiology,1997,18(4):220-223 |
| Binswanger型白质脑病危险因素的探讨 |
| A Study on the Risk Factors of Binswanger's Leukoencephalopathy (BE) |
| Received:April 12, 1996 Revised:August 28, 1996 |
| DOI： |
| KeyWord: Binswanger型白质脑病 危险因素 条件logistic回归分析 |
| English Key Word: Binswanger's leukoencephalopathy Risk factors Conditional logistic regression |
| FundProject: |
| Author Name | Affiliation | | Chen Chun-fu | Department of Neurology, Jinan Military General Hospital, jinan 250031 | | Chen Tong-hui | Department of Neurology, Jinan Military General Hospital, jinan 250031 | | Jia Hai-yan | Department of Neurology, Jinan Military General Hospital, jinan 250031 | | 郭述苏 | Department of Neurology, Jinan Military General Hospital, jinan 250031 | | 薛慎伍 | Department of Neurology, Jinan Military General Hospital, jinan 250031 | | 于金萍 | Department of Neurology, Jinan Military General Hospital, jinan 250031 | | 尚明谦 | Department of Neurology, Jinan Military General Hospital, jinan 250031 | | 曹秉振 | Department of Neurology, Jinan Military General Hospital, jinan 250031 |
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| Abstract: |
| 为了探讨Binswanger型白质脑病（BE）的危险因素，对122例BE患者进行了1：1配队的病例对照研究，资料分析采用条件logistic分析方法。单因素分析发现血管性痴呆家族史、高血压、糖尿病、冠心病、短暂性脑缺血发作、脑出血、脑梗塞、肾功能不全、饮酒、吸烟与BE发生有关联，未发现体重指数、文化程度、家庭人均收入、性格以及重大不良生活事件与BE有关联。多因素分析结果表明高血压、短暂性脑缺血发作、冠心病、血管性痴呆家族史、糖尿病等是BE较稳定的影响因素。 |
| English Abstract: |
| A matched case control study (1:1) was carried out among 122 hospitalized patients with Binswanger's leukoencephalopathy to explore the possible risk factors of BE.Data collected were processed with conditional logistic regression analysis. Individual logistic analysis showed that family history of vascular dementia,history of hypertension,diabetes,coronary heart disease,transient cerebral ischemic attacks(TIAs),cerebral ischemia,cerebral hemorrhage,renal disfunction, alcohol intake smoking were risk factors while healthy life style played protective effect.Body weight index,average family income,education level and type A behavior scores did not show close relations with BE.Multiple regression analysis showed that hypertension,TIAs,coronary heart disease,diabetes and family history of vascular dementia were independent risk factors. |
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