| 滕伟禹,王海龙,时景璞,付凌雨,李辉,董卫,董亚珞,周波,赵峰,王文利.辽宁省彰武县高血压高发地区人群脑卒中患病影响因素研究[J].Chinese journal of Epidemiology,2007,28(5):441-444 |
| 辽宁省彰武县高血压高发地区人群脑卒中患病影响因素研究 |
| Study on the influencing factors to cerebral stroke in a region with high prevalence rate of hypertension |
| Received:November 08, 2006 |
| DOI： |
| KeyWord: 脑卒中 高血压 危险因素 横断面研究 |
| English Key Word: Cerebral stroke HypertenSion Risk factor Cross—section research |
| FundProject:辽宁省教育厅基金资助项目(2004B008);辽宁省科技厅基金资助项目(2005225010) |
| Author Name | Affiliation | E-mail | | TENG Wei-yu | Department of Neurology, The First Affiliated Hospital of Chinese Medical University, Shenyang 110001, China | | | WANG Hai-long | 临床流行病教研室 | | | SHI Jing-pu | 临床流行病教研室 | sjp56@yahoo.com | | FU Ling-yu | Department of Neurology, The First Affiliated Hospital of Chinese Medical University, Shenyang 110001, China | | | LI Hui | Department of Neurology, The First Affiliated Hospital of Chinese Medical University, Shenyang 110001, China | | | DONG Wei | Department of Neurology, The First Affiliated Hospital of Chinese Medical University, Shenyang 110001, China | | | DONG Ya-luo | Department of Neurology, The First Affiliated Hospital of Chinese Medical University, Shenyang 110001, China | | | ZHOU Bo | Department of Neurology, The First Affiliated Hospital of Chinese Medical University, Shenyang 110001, China | | | ZHAO Feng | 临床流行病教研室 | | | WANG Wen-li | 临床流行病教研室 | |
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| Abstract: |
| 目的 研究辽宁省彰武县农村高血压高发地区脑卒中患病的影响因素。方法 采用整群随机抽样方法对彰武县6个乡11个村18岁以上人群5208人进行一般情况、常见脑卒中危险因素的调查，测量血压和检测血液生化指标。资料采用SPSS 10。0软件进行分析。结果 该地区脑卒中标化患病率为3。10%，性别间差异有统计学意义，患病率随年龄增加而升高;多因素分析结果显示，高血压、舒张压、脉压、年龄及高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)与脑卒中患病密切相关，OR值95%CI分别为:2。958(1。783～4。907)、2。803(1。934～4。062)、1。154(1。056～1。261)、1。080(1。063～1。097)、0。390(0。235～0。647)、1。422(1。008～2。006)。结论 高血压尤其是高舒张压、脉压、LDL-C是彰武县农村脑卒中高发的主要危险因素，HDL-C是保护因素。 |
| English Abstract: |
| Objective To investigate the influencing factors on cerebral stroke in Zhangwu county,Liaoning province, a region with high hypertension prevalence rate. Methods By cluster sampling method, 5208 adults(>18y.)from 11 villages of 6 towns were registered. General information, common risk factors of cerebral stroke about these persons was recorded. Blood pressure together with several biochemistry indicators was determined. Data were analyzed by SPSS 10. 0 software. Results Standardized prevalence of cerebral stroke in this region was 3.10%,and the difference between males and females was significant. Prevalence rate was increasing with age. Multiple-factor analysis revealed that the incidence rate of cerebral stroke was related to high blood pressure, high diastolic pressure, pulse pressure,age, high-density lipoprotein cholesterol(HDL-C) and low-DL-C(LDL-C) level with OR values of 95%CI as 2. 958(1.783-4.907)，2.803(1.934-4.062)，1.154(1.056-1.261)，1.080(1，063-1.097)，0.390(0.235-0.647) and 1.422(1.008-2.006)respectively. Conclusion High blood pressure, in particular high diastolic pressure, pulse pressure and LDL-C level were main risk factors of cerebral stroke in Zhangwu countryside. However, HDL-C level was a protective factor. No new risk factors were discovered. |
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