袁兰所,郝玉明,郑群,牟丽娜.腰臀比对女性公务员心血管病危险因素的临床预测力[J].Chinese journal of Epidemiology,2009,30(3):214-218 |
腰臀比对女性公务员心血管病危险因素的临床预测力 |
Clinical predictability of the waist-to-hip ratio in assessing the risk factors of cardiovascular disease among public servants in Shijiazhuang city |
Received:September 16, 2008 |
DOI:10.3760/cma.j.issn.0254-6450.2009.03.002 |
KeyWord: 腰臀比 心血管病危险因素 临床预测力 女性公务员 |
English Key Word: Waist-to-hip ratio Cardiovascular disease,risk factors Clinical predictability Female civil servant |
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Abstract: |
目的 评估女性公务员腰臀比(WHR)对于心血管病危险因素的临床预测价值. 方法 选择4153名高等院校2006年参加体检的女性公务员, 按WHR值定义分为4个组:<0. 80、0. 80~<0. 84、0. 84~<0. 90、≥0. 90. 每个组以健康体检方案适应的规则统计危险因素, 包括高血压、高血糖、血脂紊乱. 结果 将WHR≥0. 84与WHR<0. 80组比较, 显示血压升高(收缩压)、血脂紊乱(TG升高和HDL-C降低)、空腹血糖升高;这些变量的OR值升高与WHR<0. 80组比较差异有统计学意义. 即使校正吸烟、年龄、BMI后仍保持这种趋势. 0. 80≤WHR<0. 84组与WHR<0. 80组比较仅HDL-C显示降低. 结论 WHR≥0. 84是一个警戒线, 超过界限, 预示增加了发生心血管病的危险因素. |
English Abstract: |
Objective To assess the clinical predictability of waist-to-hip ratio(WHR)among female civil servants who had experienced risk factors of cardiovascular disease. Methods Data was gathered from 4153 female civil servants aged 21-91 y working at universities who were enrolled in health screening centre at the Second Hospital Attached to Hebei Medical University, in 2006. WHR quartiles were determined as:<0. 80, 0. 80-<0. 84, 0. 84-<0. 90 and≥0. 90. Subjects were placed into high-risk categories for cardiovascular disease on the basis of national health reference on range norms of protocol including hypertension, diabetes mellitus and dyslipidemia. Results Participants had an increased likelihood of hypertension(systolic blood pressure), dyslipidemia(elevated triacylglycerol and descending HDL-C)and diabetes mellitus at WHR≥0. 84. All aforementioned variables had a significant odds ratio at WHR≥0. 84. This trend was further persisted after adjustment had been made on smoking, age, and BMI. Descended HDL-C was observed at the 0. 80≤WHR<0. 84 when compared with WHR<0. 80. Conclusion These data indicated an upward shift in the critical threshold for WHR to≥0. 84. Above which point, there was an elevation of risk factors on cardiovascular diseases among all the female civil servants. The trend persisted regardless of smoking, BMI128 and at what age group, among the civil servants population. |
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