| 陈晓,曾志磊,谢鹏.西尼罗病毒感染的抗体检测方法研究进展[J].Chinese journal of Epidemiology,2009,30(9):969-972 |
| 西尼罗病毒感染的抗体检测方法研究进展 |
| A review on assays for detecting anfibodies of West Nile virus infection |
| Received:December 18, 2008 Revised:September 17, 2007 |
| DOI： |
| KeyWord: 西尼罗病毒 抗体 检测 |
| English Key Word: West Nile virus Antibody Detection |
| FundProject:国家“十一五”高科技发展计划(2006AA022196) |
| Author Name | Affiliation | E-mail | | CHEN Xiao | Department ofNeurology, the First Affiliated Hospital, ChongqingMedical University, Chongqing 400016, China | | | ZENG Zhilei | Department ofNeurology, the First Affiliated Hospital, ChongqingMedical University, Chongqing 400016, China | | | XIE Peng | Department ofNeurology, the First Affiliated Hospital, ChongqingMedical University, Chongqing 400016, China | peng．xie58@gmail．com |
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| Abstract: |
| 西尼罗病毒(West Nile virus，WNV)是一种单股正链RNA病毒，属黄病毒科(Family Flaviviridae)、黄病毒属(Genus Flavivirus)，与日本乙型脑炎病毒(Japanese encephalitis virus，厄V)、墨累谷脑炎病毒(Murray Valley encephalitis virus，MVEV)、圣路易斯脑炎病毒(St．Louis encephalitis virus，SLEV)、昆津病毒(Kunjin virus，KV)同属JEV血清群。病毒核酸编码3种结构蛋白和7种非结构蛋白。3种结构蛋白分别是病毒壳蛋白(c)、包膜蛋白(E)和前膜蛋白(prM)。 |
| English Abstract: |
| Objective To investigate whether green tea consumption can reduce the risk of adult leukemia. Methods A hospital-based matched case-control study was conducted in 2005一2006. We recruited 107 confirmed leukemia cases and 110 inpatient controls with orthopedic disease without leukemia or other malignancy matched on gender, age and hospitals that patients stayed. Related information were gathered on quantity, duration and frequency of tea consumption, demographic characteristics, exposure to
radiation and occupational hazards, medications, using a validated questionnaire by face-to-face interview. Univariate and multivariate unconditional logistic regression analysis were used to estimate odds ratios (ORs) and associated 95% confidence intervals(Cls) with SPSS 11.5 software. Results Compared with non-tea-drinkers, the OR of those who consumed green tea was 0. 58 ( 95 % CI:0.34-1.00，P< 0.05) under univariate statistical analysis. The OR was 0. 52 ( 95 96 CI:0.28-0.98, P=0.04)，using logistic
regression to count for age, gender, residential area, smoking, level of education, exposure to radiation, benzene and organo-phosphorus. Compared with non-drinkers, the risk of adult leukemia declined with increasing quantity,duration,and frequency of green tea consumption. Tests for trend on dose-response was statistically significant (P<0.01)Conclusion A higher consumption of green tea seemed to be associated with a declined risk of adult leukemia. Tea consumption might be of help to human health planning
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