| 唐路得,张沿君,高晓萌,董瑞,张喜凤,谷鸿喜,商庆龙.幽门螺杆菌感染与慢性荨麻疹相关性的Meta分析[J].Chinese journal of Epidemiology,2014,35(3):317-321 |
| 幽门螺杆菌感染与慢性荨麻疹相关性的Meta分析 |
| A Meta-analysis on the relations between Helicobacter PY／or／infection and chronic Urticaria |
| Received:August 29, 2013 Revised:September 12, 2012 |
| DOI： |
| KeyWord: 幽门螺杆菌 慢性荨麻疹 Meta分析 |
| English Key Word: Helicobacter pylori Chronic urticaria Meta-analysis |
| FundProject:国家自然科学基金(81000726) |
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| Abstract: |
| 目的探讨幽门螺杆菌(胛)感染与慢性荨麻疹发生的病因学关系。方法以肿、慢性荨麻疹为检索词，检索维普学术期刊数据库、中国期刊全文数据库、万方学术期刊数据库和PubMed数据库，筛选后纳入相关病例对照研究文献进行Meta分析，通过Stata软件计算合并OR值及其95%CI。结果入选研究共37项，累计慢性荨麻疹病例2 909人，对照组l 873人，数据表现为异质性。与对照组比较，胛感染增加慢性荨麻疹的发生风险(OR=3.20，95%CI：2.31～4.43)。回归分析显示检测方法和地区分布是结论的重要影响因素。结论胛感染与慢性荨麻疹发生存在相关性。研究结果与分有地区和检测方法有关。 |
| English Abstract: |
| Objective To investigate the relationship between Helicobacter pylori (Hp) infection and the development of chronic urticaria.Methods Published case-control studies which concemed HP infection related chronic urticaria were searched in Wanfang. CNKI.CQVIP Chinese data banks and PubMed. Meta-analysis was applied to analyze the pooled odds ratio(OR)and 95%confidence interval(C／).Results 37 studies which comprised 2 909 Cases ofchronic urticarla andl 873 persons served as controls were enrolled.When compared with the controls.P infectionsign ificantly increased the risk of chronic urticaria development with a pooled OR of 3~20(95%CI：2.3 1-4.43).Results from Meta.regression analyses showed that the distribution of residential areasand detection method being used were.potential influential factors.Conelusion infection seemedto be associated with an increased risk of developing the chronic urticaria. |
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