| 张方振,吴系科,袁同生,郑法扬,陈龄华.肾综合征出血热血清流行病学的研究 Ⅲ 隐性感染和家庭聚集性[J].Chinese journal of Epidemiology,1984,5(1):5-8 |
| 肾综合征出血热血清流行病学的研究 Ⅲ 隐性感染和家庭聚集性 |
| Seroepidemiological Investigation on Hemorrhagic Fever with Renal Syndrome(HFRS) |
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| Abstract: |
本文指出，通过对38户有阳性家族史和102户无阳性家族史的302个家庭成员的调查发现：
1.在农村型HFRS的流行区，普通人群存在隐性感染，其中男的隐性感染率为11.39%；女的为17.36%从年龄分布来看，29岁以下和60岁以上较高，而30~59岁者较低。其总体人群的隐性感染率为14.24%。
2.用间接荧光技术检查38户有阳性家族史的家庭成员131人，其中隐性感染者为28人，隐性感染率为21.37%，而无阳性家族史的171人中，隐性感染者为15人，隐性感染率为8.87%；卡方检验结果，P<0.01，即存在阳性家族史与家庭成员的隐性感染有极为明显的联系。
3.用二项分布式的原理进行家庭聚集性分析的结果提示，该病的感染（包括显性和隐性）具有极为明显的家庭聚集性。χ2检验P<0.01，均衡性检验可排除性别和年龄构成差异的混杂影响。 |
| English Abstract: |
This paper presented that serum samples from 131 family members living in 38 families with and 171 members of 102 families without histories of HFRS were tested.These results were:
1.The inapparent infection was found in both kind of families living in the HFRS endemic area. Inapparent infection rate in the males was 11.39%, that of the females was 17.36%. Age-specfic inapparent infection rate showed that the rate of ≥ 29 and>60 years age groups was higher than that of 30-59 years age roup with a total of 14.24%.
2.of 131 family members with history of HFRS 28 were positive (21.3%),whereas 171 members of 102 families without such history 15 were Positive (8.87%) (P<0.01). |
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