张方振,吴系科,袁同生,郑法扬,陈龄华.肾综合征出血热血清流行病学的研究 Ⅲ 隐性感染和家庭聚集性[J].Chinese journal of Epidemiology,1984,5(1):5-8 |
肾综合征出血热血清流行病学的研究 Ⅲ 隐性感染和家庭聚集性 |
Seroepidemiological Investigation on Hemorrhagic Fever with Renal Syndrome(HFRS) |
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Abstract: |
本文指出,通过对38户有阳性家族史和102户无阳性家族史的302个家庭成员的调查发现: 1.在农村型HFRS的流行区,普通人群存在隐性感染,其中男的隐性感染率为11.39%;女的为17.36%从年龄分布来看,29岁以下和60岁以上较高,而30~59岁者较低。其总体人群的隐性感染率为14.24%。 2.用间接荧光技术检查38户有阳性家族史的家庭成员131人,其中隐性感染者为28人,隐性感染率为21.37%,而无阳性家族史的171人中,隐性感染者为15人,隐性感染率为8.87%;卡方检验结果,P<0.01,即存在阳性家族史与家庭成员的隐性感染有极为明显的联系。 3.用二项分布式的原理进行家庭聚集性分析的结果提示,该病的感染(包括显性和隐性)具有极为明显的家庭聚集性。χ2检验P<0.01,均衡性检验可排除性别和年龄构成差异的混杂影响。 |
English Abstract: |
This paper presented that serum samples from 131 family members living in 38 families with and 171 members of 102 families without histories of HFRS were tested.These results were: 1.The inapparent infection was found in both kind of families living in the HFRS endemic area. Inapparent infection rate in the males was 11.39%, that of the females was 17.36%. Age-specfic inapparent infection rate showed that the rate of ≥ 29 and>60 years age groups was higher than that of 30-59 years age roup with a total of 14.24%. 2.of 131 family members with history of HFRS 28 were positive (21.3%),whereas 171 members of 102 families without such history 15 were Positive (8.87%) (P<0.01). |
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