社会经济地位、环境因素及个人行为对肺结核发病危险的研究

董碧蓉; 葛宁; 刘关键

Abstract

董碧蓉,葛宁,刘关键.社会经济地位、环境因素及个人行为对肺结核发病危险的研究[J].Chinese journal of Epidemiology,2001,22(2):102-104

社会经济地位、环境因素及个人行为对肺结核发病危险的研究

Social economical status, behaviors and environment as the risk factors of tuberculosis in ChengduChina

Received:July 20, 2000

DOI：

KeyWord: 肺结核危险因素病例对照研究

English Key Word: Pulmonary tuberculosis Risk factor Case -control study

FundProject:国际临床流行病学网( INCLEN) 资助项目( 05082)

Author Name	Affiliation
DONG Birong	INCLEN the Regional Resource and Training Center, First Affiliated Hospital, West China University of Medical Sciences, Chengdu 610041, China
GE Ning	INCLEN the Regional Resource and Training Center, First Affiliated Hospital, West China University of Medical Sciences, Chengdu 610041, China
LIU Guanjian	INCLEN the Regional Resource and Training Center, First Affiliated Hospital, West China University of Medical Sciences, Chengdu 610041, China

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Abstract:

目的探讨社会经济地位、个人行为(吸烟、饮酒)、环境因素(居住和工作环境)、体重指数(BMI)等对成都地区成人肺结核发病危险的影响，以确定该地区肺结核的主要危险因素。方法采用群体病例对照研究、多变量多指标测量、多因素分析得出结论。结果由职业、教育程度和家庭收入测量的社会经济地位、吸烟、饮酒等与肺结核发病无关;而吸烟合并饮酒者，肺结核发病危险显著增加(OR=6.12，95%CI=1.15～32.49);其他与肺结核发病相关的因素，按危险度顺位排列是暴露于化学气雾(OR=5.15，95%CI=1.44～18.40)、低BMI(OR=4.72，95%CI=2.68～8.33)、室内潮湿(OR=4.06，95%CI=2.25～7.33)和暴露于大量粉尘(OR=2.35，95%CI=1.18～4.70)。结论不良个人行为(吸烟+饮酒)，拥挤、阴暗潮湿和卫生状况差的环境，长期暴露于大量粉尘或化学气雾与成都地区成人肺结核发病有密切关系。

English Abstract:

Objective　To study the risk factors of pulmonary tuberculosis in Chengdu, Southwest China.Methods　A population -based case -control study was used which included 174 cases selected from 12 communities in Chengdu and 174 controls selected from registered population with normal chest radiograph. Cases were active TB patients which were matched for age, sex with controls, then interviewed by trained interviewers using a standardized questionnaire.Results　Social economic status measured by education, occupation and income did not show obvions influence to TB;It found that the active smoking,passive smoking, type of cigarettes and alcohol consumption had no significanct effects on TB during logistic regression analysis.The study showed that a person who was smoking and also alcohol intake had a higher risk to get TB (OR =6. 12, 95%CI =1. 15 -32. 49).Significant association was showed in the Dose -Response Analysis( OR =1. 37, 95%CI =1. 30-2. 30).Crowded living space (OR =1. 14, 95%CI =1. 05 -1. 25), degree of darkness (OR =2. 18, 95%CI =1. 11 -4. 27) and moisture (OR =4. 06,95%CI=2. 25 -7. 33), poor sanitary (OR =3. 03, 95%CI =1. 22-4. 44), airpollution of working environment, which were filled with dusts (OR =2. 35, 95%CI =1. 18-4. 70) and chemical fumes(OR =5. 15, 95%CI=1. 44 -18. 40)were strongly associated with pulmonary tuberculosis. BMI also had strong relationship with TB (OR =4. 72, 95%CI =2. 68-8. 33).Conclusion 　Poor environment and exposure to dust and chemical fume under working condition, low BMI, smoking combining alcohol consumption were the risk factors of adult pulmonary tuberculosis in Chengdu, China.

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