曾军,洪震,黄茂盛,金美华.人群癫痫危险因素及社会心理因素病例对照研究[J].Chinese journal of Epidemiology,2003,24(2):116-118 |
人群癫痫危险因素及社会心理因素病例对照研究 |
A case-control study on the risk factors and other socio-psychological factors of epilepsy |
Received:December 17, 2001 |
DOI: |
KeyWord: 癫痫 病例对照研究 危险因素 社会心理因素 |
English Key Word: Epilepsy Case control study Risk factors Socio psychological factors |
FundProject: |
Author Name | Affiliation | ZENG Jun | Department of Biostatistics and Epidemiology, Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China | HONG Zhen | Department of Biostatistics and Epidemiology, Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China | HUANG Mao sheng | Department of Biostatistics and Epidemiology, Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China | JIN Mei hua | Department of Biostatistics and Epidemiology, Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China |
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Abstract: |
目的 了解自然人群癫痫患者的危险因素及社会心理状况。方法对上海市金山区朱泾镇普查出的71例原发性癫痫患者1∶1配对进行危险因素调查及对包括10例继发性在内的癫痫患者进行配对的社会心理状况的问卷调查。结果经过多因素逐步条件logistic回归分析发现,新生儿疾病(OR=6.517)、饮酒(OR=10.761)、癫痫家族史(OR=5.414)与癫痫有着很强的关联。病例组的社会心理状况与正常对照组存在着明显的差异,在≥17岁的成人患者中尤其明显。结论新生儿疾病及产伤、饮酒、癫痫家族史是癫痫发病的危险因素,心理与精神异常在癫痫患者中发生率很高。 |
English Abstract: |
Objective To identify the risk factors and socio psychological condition of epilepsy in general population. Methods A community based, pair matched case control study using the epileptic patients living in Zhujing town, Jinshan district, Shanghai was carried out. Patients were matched for age (±1 years) and gender to controls (81 cases and 81 controls). Data was analyzed with multiple conditional logistic regression. Results As a result of multiple logistic regression, postnatal insults(OR=6.517), alcohol intake(OR = 10.761)and family history(OR = 5.414)were powerfully associated with epilepsy. Compared with control group, epileptic patients were significantly different in socio psychological condition, especially in ≥17 years adult patients. Conclusion Postnatal insults, alcohol intake and family history were the risk factors of epilepsy. Psychological and psychiatric disorders were highly prevalent among epilepsy patients. |
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