Abstract
曾军,洪震,黄茂盛,金美华.人群癫痫危险因素及社会心理因素病例对照研究[J].Chinese journal of Epidemiology,2003,24(2):116-118
人群癫痫危险因素及社会心理因素病例对照研究
A case-control study on the risk factors and other socio-psychological factors of epilepsy
Received:December 17, 2001  
DOI:
KeyWord: 癫痫  病例对照研究  危险因素  社会心理因素
English Key Word: Epilepsy  Case control study  Risk factors  Socio psychological factors
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Author NameAffiliation
ZENG Jun Department of Biostatistics and Epidemiology, Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China 
HONG Zhen Department of Biostatistics and Epidemiology, Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China 
HUANG Mao sheng Department of Biostatistics and Epidemiology, Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China 
JIN Mei hua Department of Biostatistics and Epidemiology, Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China 
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Abstract:
      目的 了解自然人群癫痫患者的危险因素及社会心理状况。方法对上海市金山区朱泾镇普查出的71例原发性癫痫患者1∶1配对进行危险因素调查及对包括10例继发性在内的癫痫患者进行配对的社会心理状况的问卷调查。结果经过多因素逐步条件logistic回归分析发现,新生儿疾病(OR=6.517)、饮酒(OR=10.761)、癫痫家族史(OR=5.414)与癫痫有着很强的关联。病例组的社会心理状况与正常对照组存在着明显的差异,在≥17岁的成人患者中尤其明显。结论新生儿疾病及产伤、饮酒、癫痫家族史是癫痫发病的危险因素,心理与精神异常在癫痫患者中发生率很高。
English Abstract:
      Objective To identify the risk factors and socio psychological condition of epilepsy in general population. Methods A community based, pair matched case control study using the epileptic patients living in Zhujing town, Jinshan district, Shanghai was carried out. Patients were matched for age (±1 years) and gender to controls (81 cases and 81 controls). Data was analyzed with multiple conditional logistic regression. Results As a result of multiple logistic regression, postnatal insults(OR=6.517), alcohol intake(OR = 10.761)and family history(OR = 5.414)were powerfully associated with epilepsy. Compared with control group, epileptic patients were significantly different in socio psychological condition, especially in ≥17 years adult patients. Conclusion Postnatal insults, alcohol intake and family history were the risk factors of epilepsy. Psychological and psychiatric disorders were highly prevalent among epilepsy patients.
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