| 郑荣远,金嵘,徐惠琴,黄文武,陈宏,邵蓓,邹有林,黄海波,邹长林,周祖木.温州地区7～16岁中小学生抽动障碍的现况调查[J].Chinese journal of Epidemiology,2004,25(9):745-747 |
| 温州地区7～16岁中小学生抽动障碍的现况调查 |
| Study on the prevalence of tic disorders in schoolchildren aged 7-16 years old in Wenzhou |
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| DOI： |
| KeyWord: 抽动障碍|患病率|横断面调查|学龄儿童 |
| English Key Word: Tic dixmders|Prevalence rate|Cross-sectional study|Schoolchild |
| FundProject: |
| Author Name | Affiliation | | ZHENG Rong-yuan | Department of Neurology, The First Affiliated Htspital of Weuzhou Mediial College, WenZhou 325000, China | | JIN Rong | 325000 温州医学院附属第一医院流行病学教研室 | | XU Hui-qiu | Department of Neurology, The First Affiliated Htspital of Weuzhou Mediial College, WenZhou 325000, China | | HUANG Wen-wu | 温州市精神病院 | | CHEN Hong | 325000 温州医学院附属第一医院精神科 | | SHAO Bei | Department of Neurology, The First Affiliated Htspital of Weuzhou Mediial College, WenZhou 325000, China | | ZOU You一lin | | | HUANG Hai-bo | Department of Neurology, The First Affiliated Htspital of Weuzhou Mediial College, WenZhou 325000, China | | ZOU Chang-lin | 325000 温州医学院附属第一医院流行病学教研室 | | ZHOU Zu-mu | 温州市疾病预防控制中心 |
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| Abstract: |
| 目的了解温州地区中小学生抽动障碍(TD)的流行病学特征. 方法 采用分层整群抽样方法, 对温州地区9742名7～16岁的中小学生进行TD横断面调查.结果 TD总患病率为104/万; 短暂性抽动障碍、慢性运动或发声抽动障碍、发声与多种运动联合抽动障碍的患病率分别为34/万、27/万、43/万; 男性TD患病率为166/万, 女性为29/万, 男性高于女性(χ2=43.96, P＜0.001, 患病率比为5.7, 95%CI:3.20～10.30), TD 三种临床亚类型的患病率均表现为男性高于女性; 平均发病年龄为(8.5±2.8)岁, 发病高峰在6～10岁, 各年龄组患病率以9～10岁组为最高(χ2=15.51, P＜0.01), 小学生TD患病率显著高于初中生(χ2=11.33, P＜0.01, 患病率比为2.2, 95%CI:1.37～3.43); 延迟诊断率69.3%, 延迟诊断时间(中位数)为1.0年. 结论 TD在温州地区儿童少年中较多见, 疾病早期漏诊现象严重, 应提高临床医生及社会公民对该病的认识, 做到早发现早治疗. |
| English Abstract: |
| Objective To study the epidemiological features of tic disorders(TD)among schoolchildren in Wenzhou area. Methods Stratified cluster sampling was carried out to investigate TD in 9742 schoolchildren aged 7 to 16 years old in Wenzhou. Results The average prevalence rate of TD among schoolage children was 104/10 000( 166J 10 000 for males, 29/10 000 for females). There was a significantly higher prevalence rate for males than that for females(X2=43.96, P<0.001，prevalence ratio = 5.7, prevalence ratio 95%CI:3.20-10. 30 ). The prevalence rates of clinical subtypes in males was significantly higher than that of females while pupils was significantly higher than that in high school students (X2=11.33, P<0.01, prevalence ratio=2.2，prevalence ratio 95%CI:1.37-3.43). Prevalence rate of transient tic disorders(TTD), chronic motor vocal tic disorder (CMVTD), tourette syndrome(TS) were 34/10 000, 27/10 000 and 43/10 000 respectively with the highest among 9-10 years old group, The mean onset age of TD was 8.5±2.8 years. The peak of onset was among 6-10 year olds. The rate of delayed diagnosis of the disorders was 69.3%and the median in delayed diagnosis was 1.0 year Conclusion TD is a common disease with high rate of misdiagnoses among schoolchildren in Wenzhou area. Physicians and population should be trained to identify the syndromes and to practice correct diagnosis and effective treatment as early as possible. |
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