| 刘学东,龙泳,段利平,曹卫东,吕亚丽,王波,阎永平,徐德忠.617例缺血型脑卒中患者生存率及死亡影响因素的回顾性研究[J].Chinese journal of Epidemiology,2007,28(4):390-393 |
| 617例缺血型脑卒中患者生存率及死亡影响因素的回顾性研究 |
| A retrospective study on the survival rate and risk factors of mortality among 617 inpatients with ischemic stroke |
| Received:January 19, 2007 |
| DOI： |
| KeyWord: 缺血型脑卒中 随访研究 预后 生存分析 |
| English Key Word: Ischemic stroke Follow—up study Prognosis survival analysis |
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| Abstract: |
| 目的<\b> 对住院缺血型脑卒中患者进行随访,描述患者病后生存状况,并分析影响死亡的危险因素.方法<\b> 回顾性收集2002年1月至2005年6月第四军医大学西京医院神经内科确诊的617例连续性缺血型脑卒中病例,采用电话、信访等方式随访患者的生存状况及死亡原因,2006年1月完成随访工作.应用Kaplan-Meier法进行生存率分析,采用Cox比例风险回归模型对影响患者死亡的危险因素进行单因素和多因素分析.结果<\b> 随访时间最长47个月,失访59例(9.5%).随访期间死亡80例,其中缺血型脑卒中60例,脑出血3例,心脏病10例,其他死因7例,中位生存时间42.16月.患者1、2、3年生存率分别为91.9%、89.4%、85.3%.单因素及多因素Cox比例风险模型显示,影响缺血型脑卒中患者死亡的主要危险因素有:高龄(RR=1.043,95% CI:1.013～1.074),Glasgow评分低(RR=0.855,95% CI:0.742～0.985),意识水平差(RR=4.085,95% CI:2.128～7.844)和存在并发症(RR=1.765,95% CI:1.108～2.812).结论<\b> 高龄、Glasgow评分低、意识水平差和存在并发症是缺血型脑卒中患者死亡的主要危险因素. |
| English Abstract: |
| Objective<\b> The purpose of this study was to describe survival status and risk factors of mortality on inpatients with ischemic stroke.Methods<\b> 617 patients with continuous ischemic stroke cases were collected from Januaoy 2002 to June 2005 retrospectively in the Department of Neurology，X玎ing Hospital，Fourth Militarv Medical University.In order to perceive relevant infOrmation on survival and the cause of death.A1l patients were foHowed through phone calls or mailing.The foUow-up program was completed in January 2006.Kaplanomeier methods were used for survival description.Monovariant and multivariant Cbx’s proportional hazard regression model were used to analyze prognostic factors on mortality.Results<\b> The 10ngest time in the follow、·up program was 47 months with 59 dropped-out cases， making the dropout rate as 9.5％.Of these patients，80 cases died during the period of study(60 for ischemic stIuke，3 for cerebral hemorrhage，1 O for cardiac disease，7 for other cause).The median survival time was 42.16 months.The survival rates of one-year，two-year and three.year period were 91.9％， 89.4％and 85.3％，respectively.Monovariant and multivariant Cox’s proportional hazard regression model showed that the risk factors associated with mortality were 01d age(RR=1.043，95％CJ：1.013-1.074)， lower G1asgow scores(RR=0.855，95％Cf：O.742-0.985)，p∞r conscious levels(RR=4.085，95％C，： 2.128-7.844)and having complication(RR=1.765，95％CJ：1.108-2.812).Conclusion<\b> The results of this study suggested that the risk factors were 01d age，lower Glasgow 8cores，pOOr conscious levels and having complication on mortality of ischemic stroke. |
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