Abstract
乔良,朱军,袁萍,代礼,王艳萍,周光宣,韩颖,刘潇霞,张驯,曹奕.采用两维图论聚类法分析中国直肠肛门闭锁/狭窄的空间分布[J].Chinese journal of Epidemiology,2009,30(2):163-166
采用两维图论聚类法分析中国直肠肛门闭锁/狭窄的空间分布
Using two-dimensional graphic cluster method to study the geographic distribution pattern of patients with anorectal atresia/stenosis,in China
Received:October 20, 2008  
DOI:
KeyWord: 直肠肛门闭锁/狭窄  两维图论聚类
English Key Word: Anorectal atresia/stenosis  Two-dimensional graphic cluster
FundProject:国家"十一五"科技支撑计划资助项目(2006BA105A01)
Author NameAffiliationE-mail
QIAO Liang Department of Epidemiology, West China School of Public Health, Sichuan University, Chengdu 610041, China  
ZHU Jun 四川大学华西第二医院中国出生缺陷监测中心 Email:zhaAuni@163.com 
YUAN Ping Department of Epidemiology, West China School of Public Health, Sichuan University, Chengdu 610041, China Email:yuanp1117@126.com 
DAI Li 四川大学华西第二医院中国出生缺陷监测中心  
WANG Yan-ping 四川大学华西第二医院中国出生缺陷监测中心  
ZHOU Gnang-xuan 四川大学华西第二医院中国出生缺陷监测中心  
HAN Ying Department of Epidemiology, West China School of Public Health, Sichuan University, Chengdu 610041, China  
LIU Xiao-xia Department of Epidemiology, West China School of Public Health, Sichuan University, Chengdu 610041, China  
ZHANG Xun Department of Epidemiology, West China School of Public Health, Sichuan University, Chengdu 610041, China  
CAO Yi Department of Epidemiology, West China School of Public Health, Sichuan University, Chengdu 610041, China  
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Abstract:
      探讨中国直肠肛门闭锁/狭窄的地理空间分布规律,为病因研究提供线索。方法利用2001-2005年中国出生缺陷监测网以医院为基础在全国对孕28周至产后7d的围产儿进行监测的数据,采用两维图论聚类分析对全国监测点按直肠肛门闭锁/狭窄的发生率进行空间归类。
English Abstract:
      investigate the geographic distribution panem of patients with anorectal atresia/stenosis in China.in order to provide clue for research on its etiology.Methods Data were collected from Chinese Birth Defects Monitoring Network(CBDMN),which was a hospital-based congenital malformations registry system.From 2001 to 2005,all fetuses with more than 28 weeks of gestation and neonates up to 7 days of age,were monitored.Two-dimensional graphic cluster method was used to divide monitoring stations into difierent classes with the incidence rates of anorectal atresia/stenosis.Results The overall incidence of anorectal atresia/stenosis was 3.17 per 10000 during 2001 to 2005.The incidence was higher in Eastern than that in Mid or Western paas of China and tbe difierence was statistically significant(z=2.50,3.69;P=0.012,<0.001).The monitoring stations were grouped into 6 classes.Class I was with Helongjiang,Jilin and Liaoling;Class Ⅱ was with Fujian,Guangdong,Hainan,Guangxi,and South Hunan and Jiangxi;ClassⅢwas with Beijing,Tianjin,Hebei,Shandong,and Noah Jiangsu and Anhui;Class Ⅳ was with Zhejiang,Shanghai,South Anhui and Jiangsu,Noah Hunan and Jiangxi,Hubei,Henan,Shanxi and Inner Mongolia,Class V was with Ningxia,Gansu and Qinghai;and Class Ⅳ was with Shaanxi,Sichuan,Chongqing,Yunnan,Guizhou.Xinjiang and Tibet.Conclusion Our findings discovered the geographic distribution patterns of patients with anorectal atresia/stenosis in China.It is important to further analyze the relevant environmental factors attached to it so a beRer regional monitoring system for anorectal atresia/stenosis can be operated.
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