| 许祥,周密,高汝钦,郭彧,田小草,卞铮,谭云龙,裴培,余灿清,汪韶洁,陈铮鸣,李立明,代表中国慢性病前瞻性研究项目协作组.中国成年人饮酒行为特征与肥胖指标的相关性研究[J].Chinese journal of Epidemiology,2019,40(7):759-764 |
| 中国成年人饮酒行为特征与肥胖指标的相关性研究 |
| Study on correlation between alcohol consumption and obesity in adults in China |
| Received:November 28, 2018 |
| DOI：10.3760/cma.j.issn.0254-6450.2019.07.005 |
| KeyWord: 饮酒 一般性肥胖 中心性肥胖 |
| English Key Word: Alcohol consumption General obesity Central obesity |
| FundProject:国家重点研发计划精准医学研究重点专项（2016YFC0900500，2016YFC0900501， 2016YFC0900504）；国家科技支撑计划（2011BAI09B01）；中国香港Kadoorie Charitable基金；英国Wellcome Trust（202922/Z/16/Z，088158/Z/09/Z，104085/Z/14/Z） |
| Author Name | Affiliation | E-mail | | Xu Xiang | School of Public Health, Qingdao University, Qingdao 266021, China
Department of China Kadoorie Biobank, Chinese Academy of Medical Sciences, Beijing 102308, China | | | Zhou Mi | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China | | | Gao Ruqin | Department of Chronic Disease Prevention and Control, Qingdao Center for Disease Control and Prevention, Qingdao Preventive Medicine Institute, Qingdao 266033, China | | | Guo Yu | Department of China Kadoorie Biobank, Chinese Academy of Medical Sciences, Beijing 102308, China | | | Tian Xiaocao | Department of Chronic Disease Prevention and Control, Qingdao Center for Disease Control and Prevention, Qingdao Preventive Medicine Institute, Qingdao 266033, China | | | Bian Zheng | Department of China Kadoorie Biobank, Chinese Academy of Medical Sciences, Beijing 102308, China | | | Tan Yunlong | Department of China Kadoorie Biobank, Chinese Academy of Medical Sciences, Beijing 102308, China | | | Pei Pei | Department of China Kadoorie Biobank, Chinese Academy of Medical Sciences, Beijing 102308, China | | | Yu Canqing | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China | yucanqing@pku.edu.cn | | Wang Shaojie | School of Public Health, Qingdao University, Qingdao 266021, China
Department of Chronic Disease Prevention and Control, Qingdao Center for Disease Control and Prevention, Qingdao Preventive Medicine Institute, Qingdao 266033, China | wshjie508@126.com | | Chen Zhengming | Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK | | | Li Liming | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China | | | for the China Kadoorie Biobank Collaborative Group | School of Public Health, Qingdao University, Qingdao 266021, China
Department of China Kadoorie Biobank, Chinese Academy of Medical Sciences, Beijing 102308, China
Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
Department of Chronic Disease Prevention and Control, Qingdao Center for Disease Control and Prevention, Qingdao Preventive Medicine Institute, Qingdao 266033, China
Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK | |
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| Abstract: |
| 目的 分析中国成年人不同饮酒行为与肥胖的关系。方法 本研究利用中国慢性病前瞻性研究基线调查数据，根据BMI和腰围（WC）分别划分一般性肥胖和中心性肥胖，采用logistic回归分析饮酒行为与一般性肥胖和中心性肥胖间的关系。结果 本研究纳入249 873名调查对象，男性饮酒量与BMI和WC间大体呈“J”形的曲线关系。以不饮酒者作为对照，少量饮酒组患一般性肥胖和中心性肥胖的比例较低，男性的OR值分别为0.65（0.59～0.71）和0.93（0.88～0.98），女性的OR值分别为0.77（0.65～0.91）和0.89（0.80～0.99）；男性大量饮酒组患一般性肥胖（OR=1.21，95% CI：1.12～1.32）和中心性肥胖（OR=1.33，95% CI：1.27～1.40）的比例最高。饮酒频率为3～5 d/周组的BMI和WC值较高，患中心性肥胖的比例也最高（男性：OR=1.23，95% CI：1.16～1.31；女性：OR=1.13，95% CI：0.99～1.28）。20岁前开始每周饮酒的男性患中心性肥胖的比例是不饮酒者的1.24倍（95% CI：1.16～1.33）。饮啤酒者患一般性肥胖的比例较低（男性：OR=0.74，95% CI：0.67～0.82；女性：OR=0.54，95% CI：0.43～0.68）。结论 少量饮酒患肥胖的比例较低，大量饮酒者患肥胖的比例较高，开始饮酒的年龄越早肥胖的比例越高。 |
| English Abstract: |
| Objective To evaluate the correlation between alcohol consumption and obesity in adults in China. Methods The information about alcohol consumption were collected at the baseline survey of the China Kadoorie Biobank. The general obesity and central obesity were defined by BMI and waist circumference (WC) respectively. Logistic regression model was employed to examine the relationship of drinking behavior with general obesity and central obesity. Results A total of 249 873 adults were included. A J-shaped relationship was observed between alcohol consumption and obesity measurement index (BMI and WC) in men. Compared with non-drinkers, the proportion of general obesity and central obesity were lower in light drinkers (men:OR=0.65, 95%CI:0.59-0.71 and OR=0.93, 95%CI:0.88-0.98; women:OR=0.77, 95%CI:0.65-0.91 and OR=0.89, 95%CI:0.80-0.99). In men, the proportion of general obesity and central obesity was highest in heavy drinkers (OR=1.21, 95%CI:1.12-1.32; OR=1.33, 95%CI:1.27-1.40). BMI and WC were higher in those with a drinking frequency of 3-5 d/week, with largest of proportion of central obesity (men:OR=1.23, 95%CI:1.16-1.31; women:OR=1.13, 95%CI:0.99-1.28). The risk for central obesity in men who began drinking every week before 20 years old was 1.24 times higher than non-drinkers (95%CI:1.16-1.33). Those who drank beer had lower proportion of general obesity (men:OR=0.74, 95%CI:0.67-0.82; women:OR=0.54, 95%CI:0.43-0.68). Conclusion The proportion of obesity was lower in light drinkers but higher in heavy drinkers; and the earlier drinking started, the higher the risk for obesity was. |
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