陕西省男男性行为人群HIV暴露前预防药物的知晓、使用意愿及使用现状分析

李翔; 赵宇博; 任强; 贾华; 陈涛; 吴谦; 常文辉

Abstract

李翔,赵宇博,任强,贾华,陈涛,吴谦,常文辉.陕西省男男性行为人群HIV暴露前预防药物的知晓、使用意愿及使用现状分析[J].Chinese journal of Epidemiology,2024,45(12):1679-1684

陕西省男男性行为人群HIV暴露前预防药物的知晓、使用意愿及使用现状分析

Awareness, willingness, and status of using HIV pre-exposure prophylaxis among men who have sex with men in Shaanxi Province

Received:June 05, 2024

DOI：10.3760/cma.j.cn112338-20240605-00331

KeyWord: 艾滋病病毒男男性行为人群暴露前预防

English Key Word: HIV Men who have sex with men Pre-exposure prophylaxis

FundProject:陕西省科技厅社会发展项目(2020SF-111)

Author Name	Affiliation	E-mail
Li Xiang	Institute of AIDS Prevention and Control, Shaanxi Provincial Centre for Disease Control and Prevention, Xi'an 710054, China
Zhao Yubo	Departmennt of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University, Xi'an 710061, China
Ren Qiang	Institute of AIDS Prevention and Control, Shaanxi Provincial Centre for Disease Control and Prevention, Xi'an 710054, China
Jia Hua	Institute of AIDS Prevention and Control, Shaanxi Provincial Centre for Disease Control and Prevention, Xi'an 710054, China
Chen Tao	Institute of AIDS Prevention and Control, Shaanxi Provincial Centre for Disease Control and Prevention, Xi'an 710054, China
Wu Qian	Departmennt of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University, Xi'an 710061, China
Chang Wenhui	Institute of AIDS Prevention and Control, Shaanxi Provincial Centre for Disease Control and Prevention, Xi'an 710054, China	429674121@qq.com

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Abstract:

目的分析陕西省MSM中HIV暴露前预防（PrEP）药物的知晓、使用意愿和使用现状及相关因素，为制定艾滋病防控策略提供参考依据。方法 2022年3-5月，在西安市MSM社会组织协助下，依托网络平台和MSM社会组织，采用横断面研究设计，方便抽样，招募MSM为研究对象，估计样本量为900人。纳入标准为年龄≥18岁的男性、最近12个月发生同性性行为、HIV阴性或感染状况不详。使用问卷星设计和制作电子调查问卷，进行匿名式自填问卷调查，收集研究对象社会人口学特征、性行为、PrEP药物知晓和使用等信息。采用logistic回归模型分析MSM对PrEP药物的知晓和使用的相关因素。采用SPSS 25.0软件进行统计学分析。结果研究对象MSM共981人，听说过PrEP药物的比例为76.55%（751/981），PrEP药物知晓率为42.51%（417/981）。在PrEP药物知晓者中，最近6个月发生同性性行为的比例为74.34%（310/417），对PrEP药物使用意愿的比例为99.03%（307/310），PrEP药物使用率为40.97%（127/310）。多因素logistic回归分析结果显示，MSM对PrEP药物知晓的相关因素包括其他民族（aOR=4.48，95%CI：1.28~15.68）、文化程度（高中/中专，aOR=3.01，95%CI：1.49~6.07；大专/本科，aOR=2.86，95%CI：1.47~5.57；研究生，aOR=5.10，95%CI：2.37~10.98）、人均月收入为5 000~10 000元（aOR=1.70，95%CI：1.00~2.88）和最近12个月做过HIV检测（aOR=1.87，95%CI：1.34~2.61）。MSM对PrEP药物使用的相关因素包括未婚（aOR=0.46，95%CI：0.26~0.81）和向专业人员咨询PrEP药物相关知识（aOR=9.56，95%CI：4.58~19.96）。结论陕西省MSM对PrEP药物的使用意愿的比例较高，但MSM对PrEP药物的知晓率和使用率均较低。应进一步提高MSM对PrEP药物相关知识的知晓水平和正确使用的行为。

English Abstract:

Objective To analyze awareness, willingness, the status of using, and related factors of HIV pre-exposure prophylaxis (PrEP) in men who have sex with men (MSM) in Shaanxi Province to provide a reference for the next step of HIV prevention and control strategy. Methods Using a cross-sectional study design from March to May 2022, with the assistance of MSM social organizations in Xi'an, relying on the network platform and MSM Social organizations, a convenient sampling method was used to recruit MSM with an estimated sample size of 900. The inclusion criteria were male aged ≥18, having had same-sex sexual intercourse in the last twelve months, HIV-negative or unknown status of infection. An electronic questionnaire was made with the help of questionnaire-star and an anonymous self-administered questionnaire was used to collect information on socio-demographic characteristics, sexual behavior, awareness and using of PrEP, etc. A logistic regression model was used to analyze related factors of PrEP awareness and use in MSM. SPSS 25.0 software was used for statistical analysis. Results Among 981 MSM subjects, 76.55% (751/981) had heard of PrEP, and 42.51% (417/981) were aware of PrEP. Among those who knew about PrEP, 74.34% (310/417) had homosexual sexual activity in the last six months, 99.03% (307/ 310) were willing to use PrEP, and 40.97% (127/310) were using PrEP. The multivariate logistic regression analysis model results showed that nationality (other ethnic groups: aOR=4.48, 95%CI: 1.28-15.68),education level (high school or technical secondary school: aOR=3.01,95%CI:1.49-6.07; universities or colleges: aOR=2.86, 95%CI: 1.47-5.57; master degree: aOR=5.10, 95%CI: 2.37-10.98), monthly income 5 000-10 000 yuan (aOR=1.70, 95%CI: 1.00-2.88), tested for HIV in the past 12 months (aOR=1.87,95%CI:1.34-2.61) were related factors of PrEP knowledge awareness. Singlehood (aOR=0.46,95%CI:0.26-0.81) and consulted professionals about PrEP (aOR=9.56,95%CI:4.58-19.96) were related factors of PrEP use. Conclusions The proportion of willingness to use PrEP was higher among MSM in Shaanxi Province, but the awareness rate and utilization rate of MSM for PrEP were low. The cognition of PrEP should be further improved to promote the correct use of PrEP among MSM.

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