| 徐慧文,孟广全,陈瑞显,苏崇瑞,王学良.e系统在HBsAg阳性各种肝病病人中的检出情况及其流行病学意义[J].中华流行病学杂志,1983,4(4):226-229 |
| e系统在HBsAg阳性各种肝病病人中的检出情况及其流行病学意义 |
| Detection of HBeAg Among Patients with Various Hepatic Diseases with HBsAg Positiveness and the Epidemiologic Significance of HBe System |
| 收稿日期: 出版日期:2021-06-09 |
| DOI： |
| 中文关键词: |
| 英文关键词: |
| 基金项目: |
|
| 摘要点击次数: 1072 |
| 全文下载次数: 259 |
| 中文摘要: |
| 本文采用琼脂扩散法检查了644份血清的HBeAg和抗-HBe系统。其中226份血清系取自病毒性肝炎或慢性肝病病人,295份为无症状的HBsAg携带者,83份为HBsAg阴性而抗-HBs阳性,58份为HBsAg和抗-HBs均为阴性病人的血清。结果表明各种肝病病人的HBeAg和抗-HBe阳性率分别为22.57%和3.98%,无症状携带者的HBeAg和抗-HBe阳性率分别为21.36%和8.47%,与病人检出率无明显差别。在HBsAg(一)但抗-HBS (+)血清中不但能检出抗-HBe,同时也检出HBeAg,阳性率分别为15.79%和13.16%。在HBsAg和抗-HBs均(一)的血清中不能检出e系统。血清中GPT值的高低与e系统的检出率无关。HBeAg在男、女两性中检出无差异(20.45%和22.99%),但抗-HBs女性高于男性(ll.22%和4.55% P<0.01)。在青少年中HBeAg检出率明显高于大年龄组。家庭中有HBeAg阳性者,其家庭成员中HBsAg阳性率明显高于HBeAg阴性家庭,但抗-HBe的存在却无何影响。 |
| 英文摘要: |
| A total of 644 sera were tested for HBeAg and anti-HBe by immunodiffusion method. The sera were made up of 226 sera from the patients with viral hepatitis or chronic liver diseases, 295 sera from asymptomatic HBsAg carriers, 38 sera with negative HBsAg but positive anti-HBs. 58 sera with both negative HBsAg and anti-HBs.The positive rates of HBeAg and anti-HBe were 22.57% and 3.98% in the patients with viral hepatitis or chronic liver diseases, 21.36% and 8.4% in asymptomatic HBsAg carriers. The differences were not statistically significant (P>0.5). The prevalence of HBeAg and anti-HBe in HBsAg was negative, but anti-HBs positive sera was 15.79% and 13.16%. HBeAg and anti-HBe were not detected in both HBsAg and anti-HBs negative sera. SGPT levels were not correlated with the presence of HBeAg and anti-HBc in the sera. The prevalence of HBeAg in males and females was almost identical (20.45% and 22.99% respectively) (P>0.05), whiie the prevalence of anti-HBe was significantly higher in females than males (11.22% and 4.55%) (P<0.01). Younger carriers tended to be more frequently HBeAg positive than elder ones (20-34% in the 0-29 year age group and 12% in those over 30 years). The HBsAg rates of the households in HBeAg positive families were much higher than those in HBeAg negative families, but the prevalence of anti-HBe in the two groups, was identical. |
|
查看全文
Html全文
查看/发表评论 下载PDF阅读器 |
|
| 关闭 |
|
|
|
