芦天林,刘玉萍,米尔英.不同滴度的HBsAg血清的中和试验分析[J].中华流行病学杂志,1983,4(6):324-325 |
不同滴度的HBsAg血清的中和试验分析 |
Neutralizing Activity of HBsAg-positive Sera with Different titre |
收稿日期: 出版日期:2021-06-09 |
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中文摘要: |
对RPHA检测HBsAg初筛滴度不同的955份血清的中和试验结果进行了分析。结果说明中和试验阳性率随初筛滴度的升高而增加。初筛效价1:4、1:8、1:16及1:32的血清中和阳性率分别为1.1%、7.1%76.7%及83.8%而初筛效价1:64及其以上血清可100%被抗HBs中和。据此建议凡初筛效价在1:32及其以下的血清必须用中和试验证实其特异性,以排除可能存在的假阳性结果。 |
英文摘要: |
955 sera giving different titers in RPHA which was used for screening HBsAg were re-tested with neutralization test. It was found that the sera with the titer of 1:4、1:8、1:16 and 1:32 in RPHA gave the positive rate of 1.1%,7.1%,76.7% and 83.8% in neutralization test respectively. All sera with the titer of or higher than 1:64 could totally be neutralized by anti-HBs. Therefore, it was recommended that all sera giving a titer of or lower than 1:32 in RPHA should be recheckedl by neutralization test to avoid the possible false results. |
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