| 中国预防医学中心流研所流行病学研究室,中国医学科学院基础所免疫室,北京市东四妇产医院.孕妇风疹感染与新生儿畸形[J].中华流行病学杂志,1984,5(4):203-205 |
| 孕妇风疹感染与新生儿畸形 |
| The Investigation of the Relationship Between Rubella Infected Pregnancies and the Occurrence of Congenital Physical Defects in New Borne Babies |
| 收稿日期: 出版日期:2021-05-29 |
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| 中文摘要: |
1981年7月至1982年2月用血凝抑制试验检查了281例年龄20~34岁妊娠5~16周的妇女风疹抗体，结果发现其中264 （94%）人阳性和37人（13.2%） IgM亦阳性。
产后追访，在281例中能追访到的计有107例，其中4人的新生儿有先天畸形。她们4人中，有3人风疹IgM阳性，1人风疹IgM阴性，但风疹总抗体滴度很高。而这次所观察的畸形类型不是通常报告的风疹病毒所致的常见的畸形，她们也没有在妊娠早期患风疹病的主诉。 |
| 英文摘要: |
From July 1981 to February 1982, 281 pregnant women aged 20~34 years old with 5~16 week gestation were examined for hemagglutinin-inhibition antibodies against rubella and 264 (94%) of them were found to be positive.Thirty seven (13.2%) women were also positive for IgM of rubella.
Of the 281 pregnant mothers examined serologically, 107 were feasible to be followed soon after postpartum and discharge from the hospital.Conge-nital physical defects were found in 4 new-borns. Three mothers with positive rubella IgM and one. mother with high antibody titer of rubella HI were found, However, the types of defects observed in this investigation were not similar to those commonly reported defects that are associated with the disease.None of these 4 mothers complained of having rubella during their early pregnancy. |
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