文章摘要
胡绪敬,王士明,奚文龙,曹元其,杨功焕,李显英,张韶声,许才华,罗龙泽,侯高隆,李怀文,周矗,井良义,陈德全,魏仪贞,庄肃慧,方国辉,康殿财.A群脑膜炎奈瑟氏菌脂多糖抗原血清学分型的流行病学意义[J].中华流行病学杂志,1986,7(1):14-16
A群脑膜炎奈瑟氏菌脂多糖抗原血清学分型的流行病学意义
Epidemiological Significance of Lipopolysaccharide Serotyping in Neisseria Meningitidis Group A
收稿日期:  出版日期:2021-05-24
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作者单位
胡绪敬 中国预防医学中心流研所 
王士明 中国预防医学中心流研所 
奚文龙 中国预防医学中心流研所 
曹元其 中国预防医学中心流研所 
杨功焕 中国预防医学中心流研所 
李显英 江西省卫生防疫站 
张韶声 江西省卫生防疫站 
许才华 四川省卫生防疫站 
罗龙泽 四川省卫生防疫站 
侯高隆 河北省卫生防疫站 
李怀文 河北省卫生防疫站 
周矗 安徽省卫生防疫站 
井良义 安徽省卫生防疫站 
陈德全 临沂地区卫生防疫站 
魏仪贞 临沂地区卫生防疫站 
庄肃慧 临沂地区卫生防疫站 
方国辉 浙江省常山县卫生防疫站 
康殿财 黑龙江省甘南县卫生防疫站 
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中文摘要:
      从江西等省收集了A群脑膜炎奈瑟氏菌324株,应用我们所报道的分型方法可以将96.91%的菌株分成三个主要的脂多糖血清型。不同地区所收集的A群菌株脂多糖血清型的地区分布是不同的,病人与其密切接触者的菌株具有相同的脂多糖血清型,L10型菌株的致病力较强,可以引起流脑流行。本文所述的分型方法操作简便,分型率高。因此,作者认为A群菌株脂多糖血清学分型具有一定的流行病学意义,此分型方法很适于流行病学调查。
英文摘要:
      324 strains of Neisseria meningitidis group A were collected from Jiangxi and other provinces in China. 96.9 per cent of them could be dividedinto three main lipopolysaccharide (LPS) serotypes with the serotyping method revised by us. Distribution of LPS serotypes was distinct among the group-A strains collected from various parts of China, and LPS serotypes of group-A strains from the patients' close contacts seemed to be identical with those of patients. The strains of L10 serotype had higher pathogenicity and could cause the prevalence of epidemic cerebrospinal menigitis in China. The serotyping method described in this paper was simple and convenient to perform and it's positive rate was very high. Therefore, the authors think that LPS serotyping of the group-A strains possesses a definite epidemiological significance and the technique of serotyping is suitable for epidemiological investigation.
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