文章摘要
张春瑶,王天根.北京市150例子宫内膜癌的病例对照研究[J].中华流行病学杂志,1989,10(4):235-237
北京市150例子宫内膜癌的病例对照研究
A Case-control Study of Endometrial Cancer in Beijing
收稿日期:  出版日期:2021-06-01
DOI:
中文关键词: 子宫内膜癌;危险因素
英文关键词: Endometrial cancer;Risk factor
基金项目:
作者单位
张春瑶 北京医科大学流行病学教研室 
王天根 北京医科大学流行病学教研室 
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中文摘要:
      本文对北京市四个城区及近郊区1982年1月1日至1985年12月31日诊断的子宫内膜癌进行了1:2配对的病例对照研究。对研究因素进行了单因素及多因素的统计分析。结果表明:与内膜癌发生有直接关联的危险因素有肥胖、未产及低产次、初潮早、肝脏疾患等。口服联合避孕药对内膜癌的发生可能具有保护作用。研究结果支持了内膜癌病因的体内孕激素缺乏而雌激素相对过剩的内分泌病因假说。
英文摘要:
      A case-control study was conducted among 150 woman suffered from endometrial cancer (EC) in Beijing from 1982.1.1~1985. 12.31 and matched with two controls from the neighbourhood to explore the risk factors for EC.
The data were analysed with X2 test and Linear Logistic Regression. Result of the study are listed:
The risk factors directly related to EC might be obesity, nulliparity and low parity, early menarche, liver diseases. The risk factors indirectly related to EC might be irregular menstruation, premenstrual tension, dysfunctional uterine bleeding.The oral combined contraceptives showed a protective effect on EC. The results of the study support the EC etiology hypothesis of ‘unopposed action of estrogen’.
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