文章摘要
刘支援,何兴舟,黄朝富,单德义.宣威肺癌危险因素的病例对照研究[J].中华流行病学杂志,1990,11(2):79-83
宣威肺癌危险因素的病例对照研究
A Case-control Study of Lung Cancer Risk Factors in Xuanwei
收稿日期:1988-04-09  出版日期:2021-06-05
DOI:
中文关键词: 肺癌  吸烟  病例对照研究  条件Logistic回归分析
英文关键词: Lung cancer  Smoking  Case-control study  Conditional logistic regression
基金项目:
作者单位
刘支援 中国预防医学科学院环境卫生与卫生工程研究所 
何兴舟 中国预防医学科学院环境卫生与卫生工程研究所 
黄朝富 云南省宣威县卫生防疫站 
单德义 云南省宣威县卫生防疫站 
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中文摘要:
      云南省宣威县是我国农村肺癌髙发地区。前一阶段研究结论认为:室内煤烟污染是其髙发的主要原因。本研究试图在平衡煤烟因素以后,研究其他因素(如吸烟等)与宣威肺癌发生的关系,进一步探索宣威肺癌髙发的原因。本研究采取个体匹配的方法,收集了110例新发的原发性肺癌病例和426个对照。经条件Logistic回归分析结果发现:除煤烟污染因素外,宣威男性肺癌与吸烟也有一定的关系。而女性肺癌与吸烟和被动吸烟无明显关系,另外也发现宣威肺癌可能有家族聚集性现象。
英文摘要:
      In Xuanwei County,Yunnan Province, lung cancer mortality is the highest in China. The former studies showed that indoor burning of "smoky" coal was an important cause for high incidence of Xuanwei lung cancer. The 1:Mi matched case-control study was undertaken to examine the association with other risk factors such as smoking. 110 cases of primary lung cancer newly diagnosed and 426 controls indiyi-dully matched were interviewed. Conditional logistic regression was employed to examine the effect modification and to control confounding. The analytic results showed that smoking was one of the risk factors of Xuanwei male lung cancer. No relation was found between passive smoking and female lung cancer. The association was observed for familial history of lung cancer.
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