文章摘要
任爱国,韩向午.饮食与食管癌关系的病例-对照研究[J].中华流行病学杂志,1991,12(4):200-204
饮食与食管癌关系的病例-对照研究
Dietary Factors and Esophageal Cancer: A Case-Control Study
收稿日期:  出版日期:2021-06-07
DOI:
中文关键词: 食管癌;病例-对照研究;条件Logistic回归模型
英文关键词: Esophageal cancer;Casecontrol study;Logistic model
基金项目:
作者单位
任爱国 华北煤炭医学院 唐山, 063000 
韩向午 华北煤炭医学院 唐山, 063000 
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中文摘要:
      本文报告的是1987年10月至1989年4月间在唐山地区进行的一次食管癌危险因素的病例-对照研究中与饮食有关部分的结果。病例(112例)为研究期间在唐山市五所医院外科及放疗科住院的新发食管癌病人。对照主要为同期上述医院外科住院的非恶性肿瘤病人。用条件Logistic回归模型对与饮食有关的因素分析表明,发霉粮食(OR=4.08)、酸菜(OR=2.57)以及热烫食物(OR=2.53)为该地区食管的危险因素。饮茶可能通过热刺激而增加食管癌的危险。蛋类(OR=0.30)及细粮(OR=0.43)则为保护性因素。
英文摘要:
      A hospital-based case-control study of 112 patients with esophageal cancer was conducted to explore the association of dietary factors with cancer of the esophagus.Each case was matched to one non-cancerous patient from surgica; department in the hospital of the same sex, age (±5 years), occupation (farmer or nonfarmer), and residence as control.Multivariate conditional logistic regression analysis showed that the consumption of moldy grains (odds ratio (OR), 4.08), pickled vegetables (OR, 2.57), tea drinking habit (OR, 5.65), and hot food consumption (OR, 2.53) were significant risk factors for esophageal cancer. Intake of eggs (OR, 0.30) and higher proportion of flour and rice in the grain ration (>30% vs. ≤ 30%) (OR, 0.43) were protective factors. Relations beween factors were also discussed in the paper.
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