| 陈惠峰,郭志宏,顾云忠,张友金,陈桂尧,杨介者,姜霞玲,沈月根,陶志华,王文刚,姚军,钱本立.新生儿乙肝疫苗第2针接种时间与免疫效果关系研究[J].中华流行病学杂志,1994,15(6):349-350 |
| 新生儿乙肝疫苗第2针接种时间与免疫效果关系研究 |
| A Study on Relation Between Effect of HB Vaccination and Time of the Second Injection |
| 收稿日期: 出版日期:2021-05-29 |
| DOI： |
| 中文关键词: 乙肝疫苗 接种时间 |
| 英文关键词: Hepatitis B vaccine Protective rate |
| 基金项目: |
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| 中文摘要: |
| 新生儿乙肝疫苗免疫接种首针“0”和第3针“6”保持不变,将第2针分为30、40、50、60天组,于第2针免后和全程免后1个月各采血检测,各组抗—HBs阳转率和滴度均无组间差异。不论HBsAg阴性和HBsAg阳性母亲组的新生儿抗—HBs消长变化均与0、1、6程序结果相似。提示对山区、海岛等受客观条件影响大的地区,新生儿乙肝疫苗第2针接种时间可在30~60天完成。 |
| 英文摘要: |
| Three kinds of hepatitis B vaccination schedule in neonates were compared. The schedule included 0, 40 day, 6 month; 0, 50 day, 6 month; 0, 60 day. 6 month; and was controlled by the 0, 30 day, 6 month schedule. The results showed that there was no statistically significant difference among three kinds of schedule, no matter who were neonates of HBs Ag-positive mother or neonates of HBsAg-negative mother. These indicated that in areas with poor condition, such as mountain, island, the second injection of hepatitis B vaccine in neonates may be completed within 30-60 days. |
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