文章摘要
张景华,袁林,杨永弘,吴广琴,余桑洁,秦宇红,高薇,Iontova IM.600名健康妊娠妇女及其所娩新生儿B族链球菌带菌情况的研究[J].中华流行病学杂志,1995,16(1):36-39
600名健康妊娠妇女及其所娩新生儿B族链球菌带菌情况的研究
Perinatal Colonization of Group B Streptococcus: A Study in 600 Cases in Beijing Tiantan Hospital
收稿日期:1994-03-23  出版日期:2021-05-20
DOI:
中文关键词: 围产期  B族链球菌  带菌率
英文关键词: Perinatal  Group B streptococcus  Carriage
基金项目:本课题得到北京市自然科学基金和卫生部科研基金资助
作者单位
张景华 北京天坛医院妇产科 100050 
袁林 北京儿科研究所微生物免疫室 
杨永弘 北京儿科研究所微生物免疫室 
吴广琴 北京天坛医院妇产科 100050 
余桑洁 北京儿科研究所微生物免疫室 
秦宇红 北京天坛医院妇产科 100050 
高薇 北京儿科研究所微生物免疫室 
Iontova IM 俄国圣彼得堡实验医学研究所WHO链球菌研究中心 
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中文摘要:
      对天坛医院600例产妇及其所娩新生儿B族链球菌(GBS)带菌情况进行调查,结果表明,8%产妇和6.7%的新生儿围产期带有GBS,总带菌率为13%。GBS阳性产妇早产和低体重儿的发生率较GBS阴性者为多,其既往发生流产的平均次数也较多。但本组没有发现GBS阳者携带者的胎膜早破和IUGR的发生率较阴性者高。分离的GBS主要为Ⅲ型,其次为Ⅰa型。抗生素敏感试验结果表明,对所有抗生素有耐药者均有一半以上菌株,其中对青霉素和庆大霉素耐药者高达90%以上,推测与国内滥用抗生素有关,将给临床选药带来一定困难,应引起重视。
英文摘要:
      An epidemiologic study of perinatal colonization of group B streptococcus(GBS)was carried out.Six hundred mother-infant pairs were studied at Beijing Tiantan Hospital.Maternal carriage rate of GBS was 8% with a neonatal colonization rate of 6.7%. Overall perinatal carriage rate was 13%. Women with perinatal colonization showed prone to have more prematured and low birth weight babies. We did not find that perinatal colonization was associated with prolonged rupture of membranes and IUGR in our study group. Serotypical study showed that most frequent GBS type isolated from the carriers was Ⅲ, followed by Ⅰa.Antibiotic sensitivity study showed that more than half of the GBS strains were resistant to the antibiotics a severe problem which might have caused by abuse in this country.
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